α-Amylase/α-Glucosidase-IN-10
α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an α-amylase and α-glucosidase inhibitor (IC50: 30.39 μM and 65.1 μM) with potential diabetes inhibitory effects. α-Amylase/α-Glucosidase-IN-10 exhibits high gastrointestinal (GI) absorption in ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) prediction. While α-Amylase/α-Glucosidase-IN-10 acts as a substrate for P-gp and does not cross the blood-brain barrier (BBB), there may be a risk of central nervous system side effects.
For research use only. We do not sell to patients.
- Formula: C33H40ClN5O5
- Molecular Weight:622.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 30.39 μM (α-Amylase); 65.1 μM (α-Glucosidase)[1]
Chemical Information
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Molecular Weight 622.15
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Formula C33H40ClN5O5
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SMILES
O=C(/C1=N\NC(COC2=C(C)C=CC=C2C[C@H]3ON([C@]4(C[C@H](C)CC[C@H]4C(C)C)N(C)C5=O)[C@@]5([H])C3)=O)NC6=C1C=CC(Cl)=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Amylase/α-Glucosidase-IN-10 Related Classifications
HY-162373 Related Classifications
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