β-Glucocerebrosidase modulator 1
Based on 1 Customer Validation
β-Glucocerebrosidase modulator 1 (Compound 28) is an allosteric modulator for β-Glucocerebrosidase with an EC50 of 9.0 μM and a Kd of 0.050 μM.
For research use only. We do not sell to patients.
- Purity: 99.01%
- CAS No.: 3080715-77-8
- Formula: C18H20F2N2O2S
- Molecular Weight:366.43
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 3080715-77-8
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Appearance Oil
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Molecular Weight 366.43
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Formula C18H20F2N2O2S
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Color Light yellow to yellow
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SMILES
CN(C[C@@H](C1=CC(C(C)=C)=CC=C1)N)S(C2=CC(F)=CC(F)=C2)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (272.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7290 mL | 13.6452 mL | 27.2903 mL | 68.2259 mL |
| 5 mM | 0.5458 mL | 2.7290 mL | 5.4581 mL | 13.6452 mL | |
| 10 mM | 0.2729 mL | 1.3645 mL | 2.7290 mL | 6.8226 mL | |
| 15 mM | 0.1819 mL | 0.9097 mL | 1.8194 mL | 4.5484 mL | |
| 20 mM | 0.1365 mL | 0.6823 mL | 1.3645 mL | 3.4113 mL | |
| 25 mM | 0.1092 mL | 0.5458 mL | 1.0916 mL | 2.7290 mL | |
| 30 mM | 0.0910 mL | 0.4548 mL | 0.9097 mL | 2.2742 mL | |
| 40 mM | 0.0682 mL | 0.3411 mL | 0.6823 mL | 1.7056 mL | |
| 50 mM | 0.0546 mL | 0.2729 mL | 0.5458 mL | 1.3645 mL | |
| 60 mM | 0.0455 mL | 0.2274 mL | 0.4548 mL | 1.1371 mL | |
| 80 mM | 0.0341 mL | 0.1706 mL | 0.3411 mL | 0.8528 mL | |
| 100 mM | 0.0273 mL | 0.1365 mL | 0.2729 mL | 0.6823 mL |