γ-Glutamyl-S-allylcysteine
Based on 1 Customer Validation
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities.
For research use only. We do not sell to patients.
- Purity: 98.83%
- CAS No.: 91216-95-4
- Formula: C11H18N2O5S
- Molecular Weight:290.34
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine; 0.1-2.5 mg/mL) inhibits the increase of fluorescence intensity at about 440 nm in a concentration-dependent manner and reduces reacted free lysine side chains[1].
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γ-Glutamyl-S-allylcysteine (2.5 mg/mL) prevents Glycation-specific decline in BSA α-helix content and increase in β-sheet in vitro[1].
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γ-Glutamyl-S-allylcysteine (2.5 mg/mL) suppresses protein crosslinking to form polymers[1].
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γ-Glutamyl-S-allylcysteine (10, 40, 160 μg/mL) shows radical-scavenging and metal-chelating capacities[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 91216-95-4
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Appearance Solid
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Molecular Weight 290.34
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Formula C11H18N2O5S
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(N[C@H](C(O)=O)CSCC=C)=O)=O
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Synonyms
L-γ-Glutamyl-(S)-Allyl-Cysteine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 33.33 mg/mL (114.80 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 25 mg/mL (86.11 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.). Nat Prod Res. 2015;29(23):2219-22. [Content Brief]
[2]. Yi-Yu Chen, et al. Enzymatic synthesis of γ-L-glutamyl-S-allyl-L-cysteine, a naturally occurring organosulfur compound from garlic, by Bacillus licheniformis γ-glutamyltranspeptidase. Enzyme Microb Technol. Jul-Aug 2015;75-76:18-24. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.4442 mL | 17.2212 mL | 34.4424 mL | 86.1059 mL |
| 5 mM | 0.6888 mL | 3.4442 mL | 6.8885 mL | 17.2212 mL | |
| 10 mM | 0.3444 mL | 1.7221 mL | 3.4442 mL | 8.6106 mL | |
| 15 mM | 0.2296 mL | 1.1481 mL | 2.2962 mL | 5.7404 mL | |
| 20 mM | 0.1722 mL | 0.8611 mL | 1.7221 mL | 4.3053 mL | |
| 25 mM | 0.1378 mL | 0.6888 mL | 1.3777 mL | 3.4442 mL | |
| 30 mM | 0.1148 mL | 0.5740 mL | 1.1481 mL | 2.8702 mL | |
| 40 mM | 0.0861 mL | 0.4305 mL | 0.8611 mL | 2.1526 mL | |
| 50 mM | 0.0689 mL | 0.3444 mL | 0.6888 mL | 1.7221 mL | |
| 60 mM | 0.0574 mL | 0.2870 mL | 0.5740 mL | 1.4351 mL | |
| 80 mM | 0.0431 mL | 0.2153 mL | 0.4305 mL | 1.0763 mL | |
| 100 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.8611 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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