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Cat. No.: HY-P5784

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δ-Buthitoxin-Hj1a

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC₅₀ of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₃₂₆H₄₈₂N₉₂O₉₆S₈
분자량:7482.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

δ-Buthitoxin-Hj1a Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

δ-Buthitoxin-Hj1a, a scorpion-venom peptide, is a potent NaV1.1 agonist with an EC₅₀ of 17nM. δ-Buthitoxin-Hj1a can be used for the Dravet syndrome (DS) research^[1].

IC₅₀ & Target^[1]

Nav1.1

17 nM (EC₅₀)

All Sodium Channel Isoforms :

Chemical Information

분자량 7482.39
화학식 C₃₂₆H₄₈₂N₉₂O₉₆S₈
Sequence

Glu-Glu-Val-Arg-Asp-Ala-Tyr-Ile-Ala-Gln-Pro-His-Asn-Cys-Val-Tyr-His-Cys-Phe-Arg-Asp-Ser-Tyr-Cys-Asn-Asp-Leu-Cys-Ile-Lys-His-Gly-Ala-Glu-Ser-Gly-Glu-Cys-Lys-Trp-Phe-Thr-Ser-Ser-Gly-Asn-Ala-Cys-Trp-Cys-Val-Lys-Leu-Pro-Lys-Ser-Glu-Pro-Ile-Lys-Val-Pro-Gly-Lys-Cys-His (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)
Sequence Shortening

EEVRDAYIAQPHNCVYHCFRDSYCNDLCIKHGAESGECKWFTSSGNACWCVKLPKSEPIKVPGKCH (Disulfide bridge:Cys14-Cys65;Cys18-Cys38;Cys24-Cys48;Cys28-Cys50)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chun Yuen Chow, et al. Venom Peptides with Dual Modulatory Activity on the Voltage-Gated Sodium Channel NaV1.1 Provide Novel Leads for Development of Antiepileptic Drugs. ACS Pharmacol Transl Sci. 2019 Nov 25;3(1):119-134. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

δ-Buthitoxin-Hj1a

All Sodium Channel Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

δ-Buthitoxin-Hj1a Related Classifications

HY-P5784 Related Classifications