1-Boc-4-bromomethylpiperidine
Based on 1 Customer Validation
1-Boc-4-bromomethylpiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 158407-04-6
- Formula: C11H20BrNO2
- Molecular Weight:278.19
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E145 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 158407-04-6
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Appearance Solid
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Molecular Weight 278.19
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Formula C11H20BrNO2
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)N1CCC(CBr)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (359.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5947 mL | 17.9733 mL | 35.9467 mL | 89.8666 mL |
| 5 mM | 0.7189 mL | 3.5947 mL | 7.1893 mL | 17.9733 mL | |
| 10 mM | 0.3595 mL | 1.7973 mL | 3.5947 mL | 8.9867 mL | |
| 15 mM | 0.2396 mL | 1.1982 mL | 2.3964 mL | 5.9911 mL | |
| 20 mM | 0.1797 mL | 0.8987 mL | 1.7973 mL | 4.4933 mL | |
| 25 mM | 0.1438 mL | 0.7189 mL | 1.4379 mL | 3.5947 mL | |
| 30 mM | 0.1198 mL | 0.5991 mL | 1.1982 mL | 2.9956 mL | |
| 40 mM | 0.0899 mL | 0.4493 mL | 0.8987 mL | 2.2467 mL | |
| 50 mM | 0.0719 mL | 0.3595 mL | 0.7189 mL | 1.7973 mL | |
| 60 mM | 0.0599 mL | 0.2996 mL | 0.5991 mL | 1.4978 mL | |
| 80 mM | 0.0449 mL | 0.2247 mL | 0.4493 mL | 1.1233 mL | |
| 100 mM | 0.0359 mL | 0.1797 mL | 0.3595 mL | 0.8987 mL |
1-Boc-4-bromomethylpiperidine Related Classifications
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