1-(Piperidin-4-yl)azetidin-3-ol
Based on 1 Customer Validation
1-(Piperidin-4-yl)azetidin-3-ol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥97.0%
- CAS No.: 1147423-04-8
- Formula: C8H16N2O
- Molecular Weight:156.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E54 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1147423-04-8
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Appearance Solid
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Molecular Weight 156.23
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Formula C8H16N2O
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SMILES
OC1CN(C1)C2CCNCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 14.29 mg/mL (91.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4008 mL | 32.0041 mL | 64.0082 mL | 160.0205 mL |
| 5 mM | 1.2802 mL | 6.4008 mL | 12.8016 mL | 32.0041 mL | |
| 10 mM | 0.6401 mL | 3.2004 mL | 6.4008 mL | 16.0020 mL | |
| 15 mM | 0.4267 mL | 2.1336 mL | 4.2672 mL | 10.6680 mL | |
| 20 mM | 0.3200 mL | 1.6002 mL | 3.2004 mL | 8.0010 mL | |
| 25 mM | 0.2560 mL | 1.2802 mL | 2.5603 mL | 6.4008 mL | |
| 30 mM | 0.2134 mL | 1.0668 mL | 2.1336 mL | 5.3340 mL | |
| 40 mM | 0.1600 mL | 0.8001 mL | 1.6002 mL | 4.0005 mL | |
| 50 mM | 0.1280 mL | 0.6401 mL | 1.2802 mL | 3.2004 mL | |
| 60 mM | 0.1067 mL | 0.5334 mL | 1.0668 mL | 2.6670 mL | |
| 80 mM | 0.0800 mL | 0.4001 mL | 0.8001 mL | 2.0003 mL |
1-(Piperidin-4-yl)azetidin-3-ol Related Classifications
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