1"-α-Azido-RDPr
1"-α-Azido-RDPr (Compound 11) is an analog of adenosine diphosphate ribose, and exhibits inhibitory efficacy against the SARS-CoV-2 nonstructural protein macodomain SARS-CoV-2 NSP3 Mac1 with an IC50 of 30 nM.
For research use only. We do not sell to patients.
- Formula: C16H26N10O13P2
- Molecular Weight:628.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
-
Molecular Weight 628.38
-
Formula C16H26N10O13P2
-
SMILES
O[C@@H]1[C@H](O)[C@@H](OP(OP(O)(OC[C@H]2O[C@H](N=[N+]=[N-])[C@H](O)[C@@H]2O)=O)(O)=O)O[C@@]1(C#N)C3=CC=C4N3N=CN=C4N.N.N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)