10-Deazaaminopterin
10-Deazaaminopterin is a potent inhibitor of dihydrofolate reductase. 10-Deazaaminopterin can used in study advanced cancer.
For research use only. We do not sell to patients.
- CAS No.: 52454-37-2
- Formula: C20H21N7O5
- Molecular Weight:439.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
1.5 nM
Compound: 10-DA (10-Deazaminopterin)
|
Concentration inhibiting L1210 cell growth in culture
Concentration inhibiting L1210 cell growth in culture
|
[PMID: 2296020] |
| L1210 | IC50 |
1.8 nM
Compound: 10-DA
|
Inhibition of growth in L1210 murine leukemia cells in culture expressed as IC50 (nM)
Inhibition of growth in L1210 murine leukemia cells in culture expressed as IC50 (nM)
|
[PMID: 8340923] |
| L1210 | IC50 |
3.7 nM
Compound: 10-DAM (Deazaaminopterin)
|
Concentration required to inhibit the growth of L1210 cells
Concentration required to inhibit the growth of L1210 cells
|
[PMID: 9022804] |
Chemical Information
-
CAS No. 52454-37-2
-
Molecular Weight 439.42
-
Formula C20H21N7O5
-
SMILES
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(CCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
10-Deazaaminopterin Related Classifications
HY-125647 Related Classifications
Powered by Bioz