2-(4-(3-Bromopropoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Based on 1 Customer Validation
2-(4-(3-Bromopropoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥97.0%
- CAS No.: 957061-13-1
- Formula: C15H22BBrO3
- Molecular Weight:341.05
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E187 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 957061-13-1
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Appearance Solid
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Molecular Weight 341.05
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Formula C15H22BBrO3
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Color Off-white to yellow
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SMILES
BrCCCOC1=CC=C(C=C1)B2OC(C)(C)C(O2)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (293.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9321 mL | 14.6606 mL | 29.3212 mL | 73.3030 mL |
| 5 mM | 0.5864 mL | 2.9321 mL | 5.8642 mL | 14.6606 mL | |
| 10 mM | 0.2932 mL | 1.4661 mL | 2.9321 mL | 7.3303 mL | |
| 15 mM | 0.1955 mL | 0.9774 mL | 1.9547 mL | 4.8869 mL | |
| 20 mM | 0.1466 mL | 0.7330 mL | 1.4661 mL | 3.6652 mL | |
| 25 mM | 0.1173 mL | 0.5864 mL | 1.1728 mL | 2.9321 mL | |
| 30 mM | 0.0977 mL | 0.4887 mL | 0.9774 mL | 2.4434 mL | |
| 40 mM | 0.0733 mL | 0.3665 mL | 0.7330 mL | 1.8326 mL | |
| 50 mM | 0.0586 mL | 0.2932 mL | 0.5864 mL | 1.4661 mL | |
| 60 mM | 0.0489 mL | 0.2443 mL | 0.4887 mL | 1.2217 mL | |
| 80 mM | 0.0367 mL | 0.1833 mL | 0.3665 mL | 0.9163 mL | |
| 100 mM | 0.0293 mL | 0.1466 mL | 0.2932 mL | 0.7330 mL |
2-(4-(3-Bromopropoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Related Classifications
HY-W101211 Related Classifications
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