2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine
2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis.
For research use only. We do not sell to patients.
- CAS No.: 114652-80-1
- Formula: C10H10F4N2O5
- Molecular Weight:314.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | EC50 |
>10 μM
Compound: 25
|
Anti hepatitis-B virus activity was evaluated in 2.2.15 cells.
Anti hepatitis-B virus activity was evaluated in 2.2.15 cells.
|
[PMID: 8709113] |
| HepG2 2.2.15 | IC50 |
>200 μM
Compound: 25
|
The growth inhibition activity for the compound was evaluated in 2.2.15 cells.
The growth inhibition activity for the compound was evaluated in 2.2.15 cells.
|
[PMID: 8709113] |
Chemical Information
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CAS No. 114652-80-1
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Molecular Weight 314.19
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Formula C10H10F4N2O5
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SMILES
O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(C(F)(F)F)C2=O)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)