1. GPCR/G Protein
  2. Platelet-activating Factor Receptor (PAFR)
  3. 2-O-Ethyl PAF C-16

2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM.

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2-O-Ethyl PAF C-16

2-O-Ethyl PAF C-16 Chemische Struktur

CAS. Nr. : 78858-42-1

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Beschreibung

2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM[1].

Cellular Effect
Cell Line Type Value Description References
CCRF-CEM IC50
2.9 μg/mL
Compound: 24
In vitro inhibition of CCRF-CEM cell proliferation
In vitro inhibition of CCRF-CEM cell proliferation
[PMID: 3783607]
Molekulargewicht

509.70

Formel

C26H56NO6P

CAS. Nr.
Appearance

Oil

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCOC[C@@H](OCC)COP(OCC[N+](C)(C)C)([O-])=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reinheit & Dokumentation

Purity: 99.9%

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  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

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Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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2-O-Ethyl PAF C-16
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