1. Cell Cycle/DNA Damage
    Cytoskeleton
    Apoptosis
  2. Microtubule/Tubulin
    Apoptosis
  3. 3-(3-Phenoxybenzyl)amino-β-carboline

3-(3-Phenoxybenzyl)amino-β-carboline 

Cat. No.: HY-150511
Handling Instructions

3-(3-Phenoxybenzyl)amino-β-carboline is a potent tubulin inhibitor. 3-(3-Phenoxybenzyl)amino-β-carboline promotes selective degradation of αβ-tubulin heterodimers. 3-(3-Phenoxybenzyl)amino-β-carboline induces G2/M phase cell cycle arrest and apoptosis. 3-(3-Phenoxybenzyl)amino-β-carboline exhibits anticancer activity.

For research use only. We do not sell to patients.

3-(3-Phenoxybenzyl)amino-β-carboline Chemical Structure

3-(3-Phenoxybenzyl)amino-β-carboline Chemical Structure

CAS No. : 1327080-54-5

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Description

3-(3-Phenoxybenzyl)amino-β-carboline is a potent tubulin inhibitor. 3-(3-Phenoxybenzyl)amino-β-carboline promotes selective degradation of αβ-tubulin heterodimers. 3-(3-Phenoxybenzyl)amino-β-carboline induces G2/M phase cell cycle arrest and apoptosis. 3-(3-Phenoxybenzyl)amino-β-carboline exhibits anticancer activity[1].

In Vitro

3-(3-Phenoxybenzyl)amino-β-carboline specifically denatures tubulin, making it prone to aggregation that predisposes it to ubiquitinylation and then degradation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

365.43

Formula

C24H19N3O

CAS No.
SMILES

C(N1)(C=NC(NCC2=CC=CC(OC3=CC=CC=C3)=C2)=C4)=C4C5=C1C=CC=C5

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Storage

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Product Name:
3-(3-Phenoxybenzyl)amino-β-carboline
Cat. No.:
HY-150511
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