3,4,5-Trimethoxyphenylacetic acid-d₂ 

3,4,5-Trimethoxyphenylacetic acid-d₂ is the deuterium labeled 3,4,5-Trimethoxyphenylacetic acid^[1]. 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline^[2].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

228.24

C₁₁H₁₂D₂O₅

344299-45-2

951-82-6

COC1=C(C(OC)=CC(C([2H])([2H])C(O)=O)=C1)OC

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Demisch L, et al. 3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans. Drug Metab Dispos. 1978 Sep-Oct;6(5):507-9.  [Content Brief]