2. PROTAC
  3. PROTAC Linkers
  4. 3,4-Dibromo-Mal-PEG2-amine

3,4-Dibromo-Mal-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (3,4-Dibromo-Mal-PEG2-amine TFA) usually boasts enhanced water solubility and stability.

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3,4-Dibromo-Mal-PEG2-amine

3,4-Dibromo-Mal-PEG2-amine 화학구조

CAS No. : 1807534-86-6

사이즈 재고
50 mg   견적 받기  
100 mg   견적 받기  
250 mg   견적 받기  

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Other In-stock Forms of 3,4-Dibromo-Mal-PEG2-amine:

Other Forms of 3,4-Dibromo-Mal-PEG2-amine:

3,4-Dibromo-Mal-PEG2-amine Related Antibodies

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  • Biological Activity

  • 순도&문서

  • References

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제품 설명

3,4-Dibromo-Mal-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3,4-Dibromo-Mal-PEG2-amine Related Antibodies
분자량

386.04

화학식

C10H14Br2N2O4
CAS No.
SMILES

O=C(C(Br)=C1Br)N(CCOCCOCCN)C1=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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3,4-Dibromo-Mal-PEG2-amine Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3,4-Dibromo-Mal-PEG2-amine1807534-86-6PROTAC LinkersInhibitorinhibitorinhibit

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상품명:
3,4-Dibromo-Mal-PEG2-amine
Cat. No.:
HY-141004
수량:
MCE Japan Authorized Agent:

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