3-Azaspiro[5.5]undecane hydrochloride
Based on 1 Customer Validation
3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 1125-01-5
- Formula: C10H20ClN
- Molecular Weight:189.73
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![3-Azaspiro[5.5]undecane hydrochloride Chemical Structure](https://file.medchemexpress.com/product_pic/hy-107755.gif "Click to View 3-Azaspiro[5.5]undecane hydrochloride Chemical Structure")
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
![3-Azaspiro[5.5]undecane hydrochloride (Standard)](https://file.medchemexpress.com/product_pic/hy-107755r.gif)
Biological Activity
IC50: 1 μM (influenza A virus M2)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
1 μM
Compound: 1
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Inhibition of Influenza A Virus M2 proton channel expressed in Xenopus laevis oocytes after 2 mins by two-electrode patch clamp assay
Inhibition of Influenza A Virus M2 proton channel expressed in Xenopus laevis oocytes after 2 mins by two-electrode patch clamp assay
|
[PMID: 21691418] |
Chemical Information
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CAS No. 1125-01-5
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Appearance Solid
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Molecular Weight 189.73
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Formula C10H20ClN
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Color White to off-white
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SMILES
[H]Cl.C12(CCNCC2)CCCCC1
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Synonyms
4,4-Pentamethylenepiperidine hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (527.06 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2706 mL | 26.3532 mL | 52.7065 mL | 131.7662 mL |
| 5 mM | 1.0541 mL | 5.2706 mL | 10.5413 mL | 26.3532 mL | |
| 10 mM | 0.5271 mL | 2.6353 mL | 5.2706 mL | 13.1766 mL | |
| 15 mM | 0.3514 mL | 1.7569 mL | 3.5138 mL | 8.7844 mL | |
| 20 mM | 0.2635 mL | 1.3177 mL | 2.6353 mL | 6.5883 mL | |
| 25 mM | 0.2108 mL | 1.0541 mL | 2.1083 mL | 5.2706 mL | |
| 30 mM | 0.1757 mL | 0.8784 mL | 1.7569 mL | 4.3922 mL | |
| 40 mM | 0.1318 mL | 0.6588 mL | 1.3177 mL | 3.2942 mL | |
| 50 mM | 0.1054 mL | 0.5271 mL | 1.0541 mL | 2.6353 mL | |
| 60 mM | 0.0878 mL | 0.4392 mL | 0.8784 mL | 2.1961 mL | |
| 80 mM | 0.0659 mL | 0.3294 mL | 0.6588 mL | 1.6471 mL | |
| 100 mM | 0.0527 mL | 0.2635 mL | 0.5271 mL | 1.3177 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
3-Azaspiro[5.5]undecane hydrochloride Related Classifications
HY-107755 Related Classifications
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