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Cat. No.: HY-W041171R

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3-Chloro-L-tyrosine (Standard)

Name: 3-Chloro-L-tyrosine (Standard)
Brand: MedChemExpress
SKU: HY-W041171R
Price: 30.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 3-Chlorotyrosine (Standard))

3-Chloro-L-tyrosine is a specific biomarker in myeloperoxidase-catalyzed oxidation. 3-Chloro-L-tyrosine can be used as a molecular marker for oxidative stress and inflammation to determine whether myeloperoxidase-mediated tyrosine chlorination occurs. 3-Chloro-L-tyrosine is therefore used in the diagnosis of chlorine poisoning in forensic toxicology and in the auxiliary diagnosis of inflammation such as colorectal cancer.

For research use only. We do not sell to patients.

Purity: 95%
CAS No.: 7423-93-0
Formula: C₉H₁₀ClNO₃
Molecular Weight:215.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Chloro-L-tyrosine (Standard) Chemical Structure

CAS No.: 7423-93-0

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 7423-93-0
Molecular Weight 215.64
Formula C₉H₁₀ClNO₃
SMILES

O=C(O)[C@@H](N)CC1=CC=C(O)C(Cl)=C1
Synonyms

3-Chlorotyrosine (Standard)
Structure Classification
- Phenols
- Monophenols
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Nishio T, et al. Determination of 3-chloro-l-tyrosine as a novel indicator of chlorine poisoning utilizing gas chromatography-mass spectrometric analysis. Leg Med (Tokyo). 2020 Nov;47:101782. [Content Brief]

[2]. Fleszar MG, et al. Simultaneous LC-MS/MS-Based Quantification of Free 3-Nitro-l-tyrosine, 3-Chloro-l-tyrosine, and 3-Bromo-l-tyrosine in Plasma of Colorectal Cancer Patients during Early Postoperative Period. Molecules. 2020 Nov 5;25(21):5158. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-Chloro-L-tyrosine (Standard)