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Cat. No.: HY-149836A

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3-MeOARh-NTR chloride

3-MeOARh-NTR chloride is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR chloride possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection.

For research use only. We do not sell to patients.

Formula: C₃₃H₃₀ClN₃O₈
Molecular Weight:632.06

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

3-MeOARh-NTR chloride Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

3-MeOARh-NTR chloride (10 μM, 30 min; cell incubated with 20% O₂ and 10% O₂ for 12 h) produces a strong fluorescence signal in living HeLa cells with decreasing oxygen contents^[1].
3-MeOARh-NTR chloride (10 μM, 30 min) produces fluorescence imaging of kidney tissues from mice with λex = 488 nm and λem=510-590 nm. Thus, 3-MeOARh-NTR chloride is a efficient probe to evaluate kidney hypoxia by NTR detection^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 632.06
Formula C₃₃H₃₀ClN₃O₈
SMILES

CC/[N+](CC)=C1C=CC2=C(C3=C(OC2=C\1)C=C(C(OC)=C3)NC(OCC4=CC=C(C=C4)[N+]([O-])=O)=O)C5=C(C=CC=C5)C(O)=O.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guo H, et al. Designing a Brightness-Restored Rhodamine Derivative by the Ortho-Compensation Effect for Assessing Drug-Induced Acute Kidney Injury. Anal Chem. 2023 May 2;95(17):6863-6870. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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