3-MeOARh-NTR
Based on 1 Customer Validation
3-MeOARh-NTR is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection.
For research use only. We do not sell to patients.
- Purity: 98.07%
- Formula: C33H30N3O8+
- Molecular Weight:596.61
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
3-MeOARh-NTR (10 μM, 30 min; cell incubated with 20% O2 and 10% O2 for 12 h) produces a strong fluorescence signal in living HeLa cells with decreasing oxygen contents[1].
3-MeOARh-NTR (10 μM, 30 min) produces fluorescence imaging of kidney tissues from mice with λex = 488 nm and λem = 510-590 nm[1].
3-MeOARh-NTR is a efficient probe to evaluate kidney hypoxia by NTR detection[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 596.61
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Formula C33H30N3O8+
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Color Pink to orange
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SMILES
CC/[N+](CC)=C1C=CC2=C(C3=C(OC2=C\1)C=C(C(OC)=C3)NC(OCC4=CC=C(C=C4)[N+]([O-])=O)=O)C5=C(C=CC=C5)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 5 mg/mL (8.38 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6761 mL | 8.3807 mL | 16.7614 mL | 41.9034 mL |
| 5 mM | 0.3352 mL | 1.6761 mL | 3.3523 mL | 8.3807 mL |
3-MeOARh-NTR Related Classifications
HY-149836 Related Classifications
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