(3R)-3-Pyrrolidinemethanol
Based on 1 Customer Validation
(3R)-3-Pyrrolidinemethanol is a molecular building block and also a PROTAC linker, which can be used for the synthesis of PROTACs, such as NRX-0492 (HY-153357).
For research use only. We do not sell to patients.
- Purity : 99.69%
- CAS No.: 110013-18-8
- Formula: C5H11NO
- Molecular Weight:101.15
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 110013-18-8
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Appearance Liquid (Density: 0.979±0.06 g/cm3)
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Molecular Weight 101.15
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Formula C5H11NO
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Color Colorless to off-white
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SMILES
OC[C@H]1CNCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 175 mg/mL (1730.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.8863 mL | 49.4315 mL | 98.8631 mL | 247.1577 mL |
| 5 mM | 1.9773 mL | 9.8863 mL | 19.7726 mL | 49.4315 mL | |
| 10 mM | 0.9886 mL | 4.9432 mL | 9.8863 mL | 24.7158 mL | |
| 15 mM | 0.6591 mL | 3.2954 mL | 6.5909 mL | 16.4772 mL | |
| 20 mM | 0.4943 mL | 2.4716 mL | 4.9432 mL | 12.3579 mL | |
| 25 mM | 0.3955 mL | 1.9773 mL | 3.9545 mL | 9.8863 mL | |
| 30 mM | 0.3295 mL | 1.6477 mL | 3.2954 mL | 8.2386 mL | |
| 40 mM | 0.2472 mL | 1.2358 mL | 2.4716 mL | 6.1789 mL | |
| 50 mM | 0.1977 mL | 0.9886 mL | 1.9773 mL | 4.9432 mL | |
| 60 mM | 0.1648 mL | 0.8239 mL | 1.6477 mL | 4.1193 mL | |
| 80 mM | 0.1236 mL | 0.6179 mL | 1.2358 mL | 3.0895 mL | |
| 100 mM | 0.0989 mL | 0.4943 mL | 0.9886 mL | 2.4716 mL |
(3R)-3-Pyrrolidinemethanol Related Classifications
HY-60263 Related Classifications
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