(3S,4R)-GNE-6893
Based on 1 Customer Validation
(3S,4R)-GNE-6893 is a potent and orally active HPK1 inhibitor. (3S,4R)-GNE-6893 can be used in research of cancer.
For research use only. We do not sell to patients.
- Purity: 99.49%
- CAS No.: 2415374-97-7
- Formula: C23H24FN5O4
- Molecular Weight:453.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
Chemical Information
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CAS No. 2415374-97-7
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Appearance Solid
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Molecular Weight 453.47
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Formula C23H24FN5O4
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Color Off-white to light yellow
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SMILES
FC1=C(N)C(C=NC(NC(O[C@H]2[C@@H](COC2)C)=O)=C3)=C3C=C1C4=CN=C(OCCN5)C5=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (220.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2052 mL | 11.0261 mL | 22.0522 mL | 55.1304 mL |
| 5 mM | 0.4410 mL | 2.2052 mL | 4.4104 mL | 11.0261 mL | |
| 10 mM | 0.2205 mL | 1.1026 mL | 2.2052 mL | 5.5130 mL | |
| 15 mM | 0.1470 mL | 0.7351 mL | 1.4701 mL | 3.6754 mL | |
| 20 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7565 mL | |
| 25 mM | 0.0882 mL | 0.4410 mL | 0.8821 mL | 2.2052 mL | |
| 30 mM | 0.0735 mL | 0.3675 mL | 0.7351 mL | 1.8377 mL | |
| 40 mM | 0.0551 mL | 0.2757 mL | 0.5513 mL | 1.3783 mL | |
| 50 mM | 0.0441 mL | 0.2205 mL | 0.4410 mL | 1.1026 mL | |
| 60 mM | 0.0368 mL | 0.1838 mL | 0.3675 mL | 0.9188 mL | |
| 80 mM | 0.0276 mL | 0.1378 mL | 0.2757 mL | 0.6891 mL | |
| 100 mM | 0.0221 mL | 0.1103 mL | 0.2205 mL | 0.5513 mL |