4-Thio-2’-deoxyuridine
Based on 1 Customer Validation
4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 5580-20-1
- Formula: C9H12N2O4S
- Molecular Weight:244.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 5580-20-1
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Appearance Solid
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Molecular Weight 244.27
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Formula C9H12N2O4S
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Color Light yellow to yellow
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SMILES
O[C@H]1C[C@H](N2C(NC(C=C2)=S)=O)O[C@@H]1CO
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Synonyms
2′-Deoxy-4-thiouridine; 4-Thiodeoxyuridine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (204.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0938 mL | 20.4692 mL | 40.9383 mL | 102.3458 mL |
| 5 mM | 0.8188 mL | 4.0938 mL | 8.1877 mL | 20.4692 mL | |
| 10 mM | 0.4094 mL | 2.0469 mL | 4.0938 mL | 10.2346 mL | |
| 15 mM | 0.2729 mL | 1.3646 mL | 2.7292 mL | 6.8231 mL | |
| 20 mM | 0.2047 mL | 1.0235 mL | 2.0469 mL | 5.1173 mL | |
| 25 mM | 0.1638 mL | 0.8188 mL | 1.6375 mL | 4.0938 mL | |
| 30 mM | 0.1365 mL | 0.6823 mL | 1.3646 mL | 3.4115 mL | |
| 40 mM | 0.1023 mL | 0.5117 mL | 1.0235 mL | 2.5586 mL | |
| 50 mM | 0.0819 mL | 0.4094 mL | 0.8188 mL | 2.0469 mL | |
| 60 mM | 0.0682 mL | 0.3412 mL | 0.6823 mL | 1.7058 mL | |
| 80 mM | 0.0512 mL | 0.2559 mL | 0.5117 mL | 1.2793 mL | |
| 100 mM | 0.0409 mL | 0.2047 mL | 0.4094 mL | 1.0235 mL |