6-Deacetyloxy-7-deacetylchisocheton
6-Deacetyloxy-7-deacetylchisocheton is a limonoid compound found in the bark of Melia azedarach. 6-Deacetyloxy-7-deacetylchisocheton exhibits cytotoxicity against cancer cells. 6-Deacetyloxy-7-deacetylchisocheton can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1558056-69-1
- Formula: C26H36O4
- Molecular Weight:412.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
>40 μM
|
Cytotoxicity against human HL-60 myeloid leukemia cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
Cytotoxicity against human HL-60 myeloid leukemia cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
|
23250810 |
| SMMC-7721 | IC50 |
>40 μM
|
Cytotoxicity against human SMMC-7721 hepatocellular carcinoma cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
Cytotoxicity against human SMMC-7721 hepatocellular carcinoma cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
|
23250810 |
| A549 | IC50 |
>40 μM
|
Cytotoxicity against human A-549 lung cancer cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
Cytotoxicity against human A-549 lung cancer cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
|
23250810 |
| MCF7 | IC50 |
>40 μM
|
Cytotoxicity against human MCF-7 breast adenocarcinoma cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
Cytotoxicity against human MCF-7 breast adenocarcinoma cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
|
23250810 |
| SW480 | IC50 |
>40 μM
|
Cytotoxicity against human SW480 colorectal cancer cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
Cytotoxicity against human SW480 colorectal cancer cells assessed by MTT assay, with IC50 value greater than 40 μM indicating inactivity.
|
23250810 |
In Vitro
6-Deacetyloxy-7-deacetylchisocheton (compound 11) exhibits no activity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells and shows no significant cytotoxicity at concentrations up to 40 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1558056-69-1
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Molecular Weight 412.57
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Formula C26H36O4
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SMILES
C[C@]12[C@@]([C@]3(C)[C@@](C[C@H]1O)(C(C)(C)C(=O)C=C3)[H])(CC[C@]4(C)C2=CC[C@]4([C@@]5(CC(=O)OC5)[H])[H])[H]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)