7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin

Cat. No.: HY-N2733: FAQs
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7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin is a coumarin, that can be isolated from campylotropis hirtella (FRANCH.) SCHINDL. 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin inhibits PSA secretion in LNCaP cells, with an IC₅₀ of 24.2 μg/mL.

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7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin Chemical Structure

CAS No. : 1092952-62-9

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Description	7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin is a coumarin, that can be isolated from campylotropis hirtella (FRANCH.) SCHINDL. 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin inhibits PSA secretion in LNCaP cells, with an IC₅₀ of 24.2 μg/mL^[1].
In Vitro	7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows the proliferation inhibitory effects on LNCaP cells, with an IC₅₀ of 61.2 μg/mL^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin Related Antibodies
Molecular Weight	300.26
Formula	C₁₆H₁₂O₆
CAS No.	1092952-62-9
SMILES	COC1=C2C(OC(C(C3=C(C=C(O)C=C3)O)=C2)=O)=CC(O)=C1
Structure Classification	Phenylpropanoids Coumarins
Initial Source	Plants Leguminosae Campylotropis hirtella (Franch.) Schindl.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Han HY, et al. Coumarins from campylotropis hirtella (FRANCH.) SCHINDL. and their inhibitory activity on prostate specific antigen secreted from LNCaP cells. Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1338-41. [Content Brief]

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin1092952-62-9OthersCoumarinPSA secretionLNCaP cellsInhibitorinhibitorinhibit

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7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin