2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species (ROS)
  4. 7-Hydroxy-4-methyl-2(1H)-quinolone

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage.

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7-Hydroxy-4-methyl-2(1H)-quinolone

7-Hydroxy-4-methyl-2(1H)-quinolone 構造式

CAS 番号 : 20513-71-7

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7-Hydroxy-4-methyl-2(1H)-quinolone 関連抗体

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製品説明

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage[1].

Cellular Effect
Cell Line Type Value Description References
H9 IC50
125 μM
Compound: 6a
Concentration required to inhibit uninfected H9 cell growth
Concentration required to inhibit uninfected H9 cell growth
[PMID: 10843202]
U-937 IC50
258.7 μM
Compound: 13
Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
Antiproliferative activity against human U937 cells assessed as incorporation of [3H]-methyl-thymidine after 12 hrs by scintillation counting
[PMID: 22925447]
U-937 CC50
>1000 μM
Compound: 13
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
[PMID: 22925447]
分子量

175.18

分子式

C10H9NO2
CAS 番号
SMILES

O=C1NC2=C(C=CC(O)=C2)C(C)=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
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7-Hydroxy-4-methyl-2(1H)-quinolone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Hydroxy-4-methyl-2(1H)-quinolone20513-71-7Reactive Oxygen Species (ROS)Hydroxylatedhydroxyl radicalsDNA damageInhibitorinhibitorinhibit

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製品名:
7-Hydroxy-4-methyl-2(1H)-quinolone
製品番号:
HY-D0113
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