(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate
Based on 1 Customer Validation
(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.78%
- CAS No.: 340187-12-4
- Formula: C17H16BrNO2
- Molecular Weight:346.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E24 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 340187-12-4
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Appearance Solid
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Molecular Weight 346.22
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Formula C17H16BrNO2
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Color White to off-white
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SMILES
O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCCBr
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (288.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8883 mL | 14.4417 mL | 28.8834 mL | 72.2084 mL |
| 5 mM | 0.5777 mL | 2.8883 mL | 5.7767 mL | 14.4417 mL | |
| 10 mM | 0.2888 mL | 1.4442 mL | 2.8883 mL | 7.2208 mL | |
| 15 mM | 0.1926 mL | 0.9628 mL | 1.9256 mL | 4.8139 mL | |
| 20 mM | 0.1444 mL | 0.7221 mL | 1.4442 mL | 3.6104 mL | |
| 25 mM | 0.1155 mL | 0.5777 mL | 1.1553 mL | 2.8883 mL | |
| 30 mM | 0.0963 mL | 0.4814 mL | 0.9628 mL | 2.4069 mL | |
| 40 mM | 0.0722 mL | 0.3610 mL | 0.7221 mL | 1.8052 mL | |
| 50 mM | 0.0578 mL | 0.2888 mL | 0.5777 mL | 1.4442 mL | |
| 60 mM | 0.0481 mL | 0.2407 mL | 0.4814 mL | 1.2035 mL | |
| 80 mM | 0.0361 mL | 0.1805 mL | 0.3610 mL | 0.9026 mL | |
| 100 mM | 0.0289 mL | 0.1444 mL | 0.2888 mL | 0.7221 mL |
(9H-Fluoren-9-yl)methyl (2-bromoethyl)carbamate Related Classifications
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