Dorstenia mannii Hook.f.
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Dorstenia mannii Hook.f. (4)
- Formula: C21H20O4
- Molecular Weight: 336.38
4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model.
- Formula: C25H28O6
- Molecular Weight: 424.49
6,8-Diprenyleriodictyol is a flavonoid and bactericidal agent. 6,8-Diprenyleriodictyol can be isolated from the aerial parts of D. mannii. 6,8-Diprenyleriodictyol shows significant antibacterial activity against S. aureus including MRSA strains.
- Formula: C20H20O4
- Molecular Weight: 324.37
Dorsmanin A is a prenylated flavonoid from the twigs of Dorstenia mannii.
- Formula: C25H26O6
- Molecular Weight: 422.47
DorsmaninI is a flavonoid product that can be isolated from Dorstenia mannii.
