- Natural Products
- Plants
- Convolvulaceae
- Erycibe ferruginea C. Y. Wu
Erycibe ferruginea C. Y. Wu
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Erycibe ferruginea C. Y. Wu (2)
- Formula: C23H24O6
- Molecular Weight: 396.43
Dihydrorotenone is an insecticide and irreversible inhibitor of mitochondrial complex I. Dihydrorotenone may induce Parkinson's disease. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway. The oral LD50 of dihydrorotenone in rats is approximately 2.5 g/kg. Dihydrorotenone exhibits insecticide activity and cytotoxicity to plasma cells. Dihydrorotenone can be used to establish animal models of Parkinson's disease, safety assessment of natural pesticides, and potential cancer chemoprevention studies.
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- Formula: C16H14O6
- Molecular Weight: 302.28
1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect.
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