2. Signaling Pathways
  3. Apoptosis
  4. DAPK
  5. DAPK1 Isoform
  6. DAPK1 Activator

DAPK1 Activator

DAPK1 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-123581
    Quinocetone
    		Activator 98.25%
    Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the ATF6/DAPK1 pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage.