Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
Verweise:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Verwandte Produkte (4738)
Verwandte Produkte (4738)
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Sulfiram
0 ImagesSulfiram is a very weak aldehyde dehydrogenase (ALDH) inhibitor, with an IC50 value of 413 μM against Saccharomyces cerevisiae ALDH. As a photochemical precursor, Sulfiram undergoes photoconversion to form Disulfiram (HY-B0240), a potent ALDH inhibitor. Sulfiram inhibits the dimerization of the extracellular domain fragment (amino acid residues 230-624) of amyloid precursor protein (APP), alters the monomer-dimer equilibrium, induces conformational changes in the fragment, and enhances the production of sAPPα via α-cleavage of APP. Sulfiram can be used in research related to scabies and Alzheimer's disease.
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Quetiapine impurity 15
0 ImagesArt. -Nr.: HY-W801766CAS. Nr.: 329216-69-5Quetiapine impurity 15 is an impurity of Quetiapine.
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Moxifloxacin impurity 7
0 ImagesArt. -Nr.: HY-Z11757CAS. Nr.: 1179992-99-4Moxifloxacin impurity 7 is an impurity of Moxifloxacin.
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5-(2-Aminopyridyl)amide oxime
0 Images5-(2-Aminopyridyl)amide oxime is a synthetic intermediate useful for pharmaceutical synthesis.
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Sildenafil impurity 2
0 ImagesArt. -Nr.: HY-W109161CAS. Nr.: 268204-00-8
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Edoxaban impurity 3
0 ImagesArt. -Nr.: HY-W057728CAS. Nr.: 1392745-70-8Edoxaban impurity 3 is an impurity of Edoxaban.
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Tamsulosin impurity 16
0 ImagesArt. -Nr.: HY-W725631CAS. Nr.: 1027854-97-2Tamsulosin impurity 16 is an impurity of Tamsulosin.
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Sildenafil impurity 15
0 ImagesArt. -Nr.: HY-W700779CAS. Nr.: 139756-31-3Sildenafil impurity 15 is an impurity of Sildenafil.
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(3R,5S,E)-3,5-Dihydroxy-7-(4-isopropyl-2-(N-methylmethylsulfonamido)-6-phenylpyrimidin-5-yl)hept-6-enoic acid (Rosuvastatin Impurity)
0 ImagesArt. -Nr.: HY-Z8676CAS. Nr.: 847849-66-5(3R,5S,E)-3,5-Dihydroxy-7-(4-isopropyl-2-(N-methylmethylsulfonamido)-6-phenylpyrimidin-5-yl)hept-6-enoic acid (Rosuvastatin Impurity) is an impurity of (3R,5S,E)-3,5-Dihydroxy-7-(4-isopropyl-2-(N-methylmethylsulfonamido)-6-phenylpyrimidin-5-yl)hept-6-enoic acid (Rosuvastatin).
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Dabigatran impurity 29
0 ImagesArt. -Nr.: HY-Z1936CAS. Nr.: 1642853-67-5Synonyms: Dabigatran iMpurity F
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Dabigatran impurity 8
0 ImagesArt. -Nr.: HY-21609CAS. Nr.: 1408238-40-3
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Hancockiamide D
0 ImagesArt. -Nr.: HY-N19181CAS. Nr.: 2758265-37-9Hancockiamide D is a phenylpropanoid piperazine alkaloid found in the Australian soil fungus Aspergillus hancockii. Hancockiamide D induces cytotoxic activity in cancer cells and shows no activity in fibroblasts. Hancockiamide D can be used for the research of murine myeloma.
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Trazodone impurity 9
0 ImagesArt. -Nr.: HY-W749264CAS. Nr.: 2727463-29-6Trazodone impurity 9 is an impurity of Trazodone.
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Ranitidine impurity 3
0 ImagesArt. -Nr.: HY-Z8388CAS. Nr.: 1331637-48-9Synonyms: Ranitidine impurity JRanitidine impurity 3 (Ranitidine impurity J) is an impurity of Ranitidine.
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2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid
0 ImagesArt. -Nr.: HY-114756CAS. Nr.: 34418-48-92-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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Ramipril impurity 5
0 ImagesArt. -Nr.: HY-W008300CAS. Nr.: 87269-87-2Ramipril impurity 5 is an impurity of Ramipril.
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Sertraline impurity 3
0 ImagesArt. -Nr.: HY-W702206CAS. Nr.: 1198084-29-5Sertraline impurity 3 is an impurity of Sertraline.
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((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (N-(2-(2-(((N,N-bis(2-(((4-nitrophenoxy)carbonyl)oxy)ethyl)sulfamoyl)carbamoyl)oxy)ethoxy)ethyl)sulfamoyl)carbamate
![((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (N-(2-(2-(((N,N-bis(2-(((4-nitrophenoxy)carbonyl)oxy)ethyl)sulfamoyl)carbamoyl)oxy)ethoxy)ethyl)sulfamoyl)carbamate](https://file.medchemexpress.com/product_pic/hy-402912.gif "Click to View ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (N-(2-(2-(((N,N-bis(2-(((4-nitrophenoxy)carbonyl)oxy)ethyl)sulfamoyl)carbamoyl)oxy)ethoxy)ethyl)sulfamoyl)carbamate Product Detail")
0 ImagesArt. -Nr.: HY-402912CAS. Nr.: 1898181-67-3((1R,8S,9s)-Bicyclonon-4-yn-9-yl) methyl (N-(2-(2-(((N,N-bis (2-(((4-nitrophenoxy) carbonyl) oxy) ethyl) sulfamoyl) carbamoyl) oxy) ethoxy) ethyl) sulfamoyl) carbamate is a bifunctional linker component containing a bicyclonon-4-yne click probe and a hydrophilic carbamoyl sulfamide group, which is used for the synthesis of antibody-drug conjugates.
