Nucleoside Antimetabolite/Analog
Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands. Less selective nucleoside analogues are used as chemotherapy agents to treat cancer, eg gemcitabine and 5-FU. Antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid. The presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer.
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Nucleoside Antimetabolite/Analog Related Products (2435)
Related Products (2435)
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Sp-dGTPαS tetrasodium
0 ImagesCat. No.: HY-137618A
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8(Z),11(Z),14(Z)-Heptadecatrienoic acid
0 ImagesCat. No.: HY-N16241CAS No.: 22324-72-7Synonyms: Norlinolenic acid8(Z),11(Z),14(Z)-Heptadecatrienoic acid (Norlinolenic acid) is a fatty acid.
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1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil
![1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil](https://file.medchemexpress.com/product_pic/hy-154587.gif "Click to View 1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil Product Detail")
0 ImagesCat. No.: HY-154587CAS No.: 2095417-38-01-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
0 ImagesCat. No.: HY-W354644CAS No.: 59892-36-31-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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5’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl) inosine
0 ImagesCat. No.: HY-1543655’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl) inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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8-(Phenylmethoxy)guanosine
0 Images8-(Phenylmethoxy)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
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1-Methyl-2'-O-methylinosine
0 ImagesCat. No.: HY-152499CAS No.: 65150-69-81-Methyl-2'-O-methylinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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N1-Ethoxymethyl pseudouridine
0 ImagesCat. No.: HY-152345N1-Ethoxymethyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3’-Deoxy-3’-fluoro-5-methoxyluridine
0 ImagesCat. No.: HY-152761CAS No.: 2072145-76-53’-Deoxy-3’-fluoro-5-methoxyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
![6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-154122.gif "Click to View 6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Product Detail")
0 ImagesCat. No.: HY-1541226-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects.
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3',5'-Di-O-benzoyl fialuridine
0 ImagesCat. No.: HY-154589CAS No.: 97614-45-43',5'-Di-O-benzoyl fialuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethylammonium
0 ImagesCat. No.: HY-1541592’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2-Methoxy-estradiol-17beta 3-glucuronide
0 ImagesCat. No.: HY-180679CAS No.: 52718-01-12-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite.
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3’-O-Levulinyl-2’-deoxyadenosine
0 ImagesCat. No.: HY-154303CAS No.: 440327-45-73’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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6-Cl-PuTP tetrasodium
0 ImagesCat. No.: HY-134404A6-Cl-PuTP tetrasodium is a 6-chloropurine nucleotide can be used in the synthesis of cytokinins with anticancer activity.
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2’-Bromo-2’-deoxy-5-methyluridine
0 ImagesCat. No.: HY-154642CAS No.: 95585-76-52’-Bromo-2’-deoxy-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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4α-Carboxy-stigmasta-7,24(24(1))-dien-3β-ol
0 ImagesCat. No.: HY-180598CAS No.: 242149-51-54α-Carboxy-stigmasta-7,24(24(1))-dien-3β-ol is a carboxysterol.
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5’(R)-C-Methyladenosine
0 Images5’(R)-C-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2-Chloro-3′-deoxyadenosine
0 ImagesCat. No.: HY-154520CAS No.: 115044-75-22-Chloro-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2′-Deoxy-6-thioinosine
0 Images2′-Deoxy-6-thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
