Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2483)
Related Products (2483)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Ipflufenoquin (Standard)
0 ImagesCat. No.: HY-134338RCAS No.: 1314008-27-9(R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19.
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Antiparasitic agent-16
0 ImagesCat. No.: HY-149080CAS No.: 3046451-89-9Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC50s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC50s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes.
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6-O-Methylcatalpol
0 Images6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC50: 32.5 and 8.3 μg/mL).
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Antitrypanosomal agent 7
0 ImagesCat. No.: HY-147550CAS No.: 2492436-38-9Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA.
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Anti-infective agent 6
0 ImagesCat. No.: HY-151612CAS No.: 2839192-35-5Anti-infective agent 6 (compound 28) is a potent anti-infectious agent. Anti-infective agent 6 shows a good activity against P. falciparum F32-ART (IC50=1.4 μM) with a good selectivity index (SI>36). Anti-infective agent 6 also shows a potency against L. donovani (IC50=3.5 μM).
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Oxibendazole (Standard)
0 ImagesOxibendazole (Standard) is the analytical standard of Oxibendazole. This product is intended for research and analytical applications. Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities.
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Metronidazole Benzoate (Standard)
0 ImagesSynonyms: Benzoyl metronidazole (Standard)Metronidazole Benzoate (Standard) is the analytical standard of Metronidazole Benzoate. This product is intended for research and analytical applications. Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent.
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Chloranthalactone C
0 ImagesCat. No.: HY-N16123CAS No.: 73215-91-5Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research.
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Antimalarial agent 15
0 ImagesCat. No.: HY-150065CAS No.: 956928-33-9
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OAT-2068
0 ImagesCat. No.: HY-125279CAS No.: 2221950-65-6OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases.
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Arteflene
0 ImagesCat. No.: HY-106848CAS No.: 123407-36-3Synonyms: Ro 42-1611Arteflene is a synthetic structural analogue of artemisinin. Arteflene has antimalarial activity.
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Lunarine
0 ImagesCat. No.: HY-129278CAS No.: 24185-51-1Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM.
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Symetine dihydrochloride
0 ImagesCat. No.: HY-101590ACAS No.: 5585-62-6Synonyms: L 16726 dihydrochloride
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Sphynolactone-7
0 ImagesCat. No.: HY-125284CAS No.: 2305752-57-0Synonyms: SPL7Sphynolactone-7 (SPL7) is an active site-targeting and selective strigolactone receptor (ShHTL7) agonist. Sphynolactone-7 is effective for reducing Striga parasitism without impinging on host strigolactone-related processes.
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SID 24785302
0 ImagesCat. No.: HY-169728CAS No.: 378197-09-2SID 24785302 is a hexokinase inhibitor with antiparasitic activity. SID 24785302 exhibits activity against T. brucei and Leishmania. SID 24785302 can be used for the research of mitochondrial DNA disorders and parasitic infection.
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Pyrantel
0 ImagesCat. No.: HY-12641ACAS No.: 15686-83-6Pyrantel is an orally active antiparasitic agent. Pyrantel induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel eliminates both immature and mature endoparasites in horses. Pyrantel can be used in research related to parasitic infections.
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SL-IN-1
0 ImagesCat. No.: HY-162522SL-IN-1 (Compound C6) is an inhibitor for plant hormone steroid lactones receptor (SL receptor). SL-IN-1 promotes rice tillering, inhibits the germination of the root parasite P. aegyptiaca seeds (IC50 is 82.8 µM), delays dark-induced senescence of rice leaves, and protects the leaf membrane from lipid peroxidation.
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Trypanothione synthetase-IN-3
0 ImagesCat. No.: HY-151151CAS No.: 1314875-96-1Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum.
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Diamfenetide (Standard)
0 ImagesCat. No.: HY-119893RCAS No.: 36141-82-9Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
