Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2481)
Related Products (2481)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Efavirenz (Standard)
0 ImagesSynonyms: DMP 266 (Standard); EFV (Standard); L-743726 (Standard)Efavirenz (Standard) is the analytical standard of Efavirenz. This product is intended for research and analytical applications. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
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Hederacolchiside A1 (Standard)
0 ImagesCat. No.: HY-N6950RCAS No.: 106577-39-3Hederacolchiside A1 (Standard) is the analytical standard of Hederacolchiside A1. This product is intended for research and analytical applications. Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro.
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Antileishmanial agent-2
0 ImagesCat. No.: HY-132905CAS No.: 2863687-18-5Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
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Antitrypanosomal agent 2
0 ImagesCat. No.: HY-136200CAS No.: 475626-30-3Antitrypanosomal agent 2 is a potent and selective trypanosoma brucei inhibitor.
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LC-61
0 ImagesCat. No.: HY-180130CAS No.: 2195159-10-3LC-61 is a potent antileishmanial agent with an IC50 of 0.076 µM against intracellular L. infantum.
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Nifuratel (Standard)
0 ImagesSynonyms: NF 113 (Standard); SAP 113 (Standard); Methylmercadone (Standard)Nifuratel (Standard) is the analytical standard of Nifuratel. This product is intended for research and analytical applications. Nifuratel (NF 113, SAP 113) is a broad-spectrum antibiotic with activity against bacteria, fungi and trichomonas.
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Anti-Trypanosoma cruzi agent-8
0 ImagesCat. No.: HY-181516Anti-Trypanosoma cruzi agent-8 is an anti-Trypanosoma agent and also a Trypanosoma cruzi trypanothione reductase (TcTR) inhibitor, with an IC50 of 3.9 μM against TcTR. Anti-Trypanosoma cruzi agent-8 functionally inhibits the enzymatic activity of TcTR. Anti-Trypanosoma cruzi agent-8 exhibits trypanocidal activity against intracellular Trypanosoma cruzi amastigotes.
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PDEB1-IN-1
0 ImagesCat. No.: HY-116045CAS No.: 1622300-88-2PDEB1-IN-1 (Compound 12b) is the derivative of Cilomilast (HY-10790), and serves as an inhibitor for TryPanosoma Brucei PDEB1 (TbrPDEB1) with an IC50 of 0.95 μM. PDEB1-IN-1 inhibits the proliferation of T. Brucei with an EC50 of 26 μM.
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TgCDPK1-IN-1
0 ImagesCat. No.: HY-184426TgCDPK1-IN-1 is an orally active, blood-brain barrier-permeable TgCDPK1 inhibitor (IC50 = 15.7 nM) with antiparasitic activity against Toxoplasma gondii. TgCDPK1-IN-1 inhibits Src and TgCDPKG128M. TgCDPK1-IN-1 cures acute toxoplasmosis in immunocompetent mice and prolongs the survival of immunocompromised mice. TgCDPK1-IN-1 is applicable for research related to toxoplasmosis.
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KDU731 (Standard)
0 ImagesCat. No.: HY-103583RCAS No.: 1610610-48-4KDU731 (Standard) is the analytical standard of KDU731 (HY-103583). This product is intended for research and analytical applications. KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo. KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety.
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Diethyl phosphate-13C4 sodium
0 ImagesCat. No.: HY-W778140CAS No.: 1329613-90-2Diethyl phosphate-13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate-13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos.
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Nummularine B
0 ImagesCat. No.: HY-P2209CAS No.: 53947-96-9Synonyms: Daechuine S27; N-Demethylamphibine HNummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis.
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Antiparasitic agent-29
0 ImagesCat. No.: HY-178064Antiparasitic agent-29 (Compound 5) is a Trypanosome alternative oxidase (TAO) inhibitor with an IC50 of 1.3 nM in Trypanosoma brucei. Antiparasitic agent-29 has a broad-spectrum antiparasitic activity against Trypanosoma and Leishmania spp. Antiparasitic agent-29 accumulates in parasite mitochondria, selectively disrupting its energy metabolism and has potent membrane-perturbing activity with no cross-resistance. Antiparasitic agent-29 shows low ecotoxicity in zebrafish and Daphnia magna models. Antiparasitic agent-29 can be used for parasitic diseases like surra and dourine research.
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Propargite (Standard)
0 ImagesPropargite (Standard) is the analytical standard of Propargite. This product is intended for research and analytical applications. Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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3-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol
0 ImagesCat. No.: HY-N13116CAS No.: 76663-56-43-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol (compound 2) is a diterpenoid with antinematode activity, which can be isolated from Euphorbia kansui.
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Insecticidal agent 13
0 ImagesCat. No.: HY-163776CAS No.: 3007662-84-9Insecticidal agent 13 (compound A15) is a phenylpyrazole derivative with insecticidal and acaricidal activities, which can be used in the research of agricultural pest control.
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Isethionic acid sodium (Standard)
0 ImagesSynonyms: 2-Hydroxyethanesulfonic acid sodium (Standard); Sodium isethionate (Standard)Isethionic acid sodium salt (Standard) (2-Hydroxyethanesulfonic acid sodium (Standard); Sodium isethionate (Standard)) is the analytical standard of Isethionic acid sodium salt (HY-Y1173). This product is intended for research and analytical applications. Isethionic acid sodium salt (Sodium 1-hydroxy-2-ethanesulfonate; Sodium 2-hydroxy-1-ethanesulfonate; Sodium 2-hydroxyethanesulfonate) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid sodium salt forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid sodium salt enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis.
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Oxfendazole (Standard)
0 ImagesOxfendazole (Standard) is the analytical standard of Oxfendazole. This product is intended for research and analytical applications. Oxfendazole is the sulfoxide form of fenbendazole, which fights parasites.
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Pyronaridine tetraphosphate (Standard)
0 ImagesPyronaridine (tetraphosphate) (Standard) is the analytical standard of Pyronaridine (tetraphosphate). This product is intended for research and analytical applications. Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection.
