76748-86-2
76748-86-2
Chemical Structure
Pyronaridine tetraphosphate
- CAS No.: 76748-86-2
- Formula:C29H44ClN5O18P4
- Molecular Weight:910.03
IUPAC Name: 4-((7-chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino)-2,6-bis(pyrrolidin-1-ylmethyl)phenol tetrakis(phosphate)
InChIKey: YKUQEKXHQFYULM-UHFFFAOYSA-N
SMILES: OC1=C(CN2CCCC2)C=C(NC3=C4N=C(OC)C=CC4=NC5=CC(Cl)=CC=C53)C=C1CN6CCCC6.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
Biological Activity: Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pyronaridine tetraphosphate | 99.57% | Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection. | ||||||||||||||||||||
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Pyronaridine tetraphosphate (Standard) | ≥98% | Pyronaridine (tetraphosphate) (Standard) is the analytical standard of Pyronaridine (tetraphosphate). This product is intended for research and analytical applications. Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection. | ||||||||||||||||||||
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Pyronaridine-d4 tetraphosphate | 97.00% | Pyronaridine-d4 (tetraphosphate) is the deuterium labeled Pyronaridine tetraphosphate. Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection. | ||||||||||||||||||||
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Pyronaridine-13C2,d4 tetraphosphate | Pyronaridine tetraphosphate-13C2,d4 is the deuterium and 13C-labeled Pyronaridine tetraphosphate (HY-14749A). Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection. | |||||||||||||||||||||
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References
- [1]. Vivas L, et al. Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta Trop. 2008 Mar;105(3):222-8. [Content Brief]
- [2]. Jun Li, et al. Old drug repurposing for neglected disease: Pyronaridine as a promising candidate for the treatment of Echinococcus granulosus infections. EBioMedicine. 2020 Apr;54:102711. [Content Brief]
