Piperaquine tetraphosphate
Based on 1 publication(s) in Google Scholar
Piperaquine tetraphosphate is a potent antimalaria agent. Piperaquine tetraphosphate shows inhibition for chloroquine-sensitive and the chloroquine-resistant isolates. Piperaquine tetraphosphate in combination with dihydroartemisinin has the potential for the research of chloroquine-resistant malaria.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 911061-10-4
- Formel: C29H44Cl2N6O16P4
- Molecular Weight:927.49
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Piperaquine tetraphosphate
MoreAlle Parasite Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Piperaquine tetraphosphate shows high active against all Cameroonian isolates with IC50 of 38.9 nM, range, 7.76-78.3 nM, and shows inhibits against the chloroquine-sensitive and the chloroquine-resistant isolates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS. Nr. 911061-10-4
-
Molecular Weight 927.49
-
Formel C29H44Cl2N6O16P4
-
SMILES
ClC1=CC=C2C(N3CCN(CCCN4CCN(C5=CC=NC6=CC(Cl)=CC=C56)CC4)CC3)=CC=NC2=C1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
Reinheit & Dokumentation
Verweise
[1]. asco LK, et al. In vitro activities of piperaquine and other 4-aminoquinolines against clinical isolates of Plasmodium falciparum in Cameroon. Antimicrob Agents Chemother. 2003 Apr;47(4):1391-4. [Content Brief]
[2]. Salman S,et al. Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria. Antimicrob Agents Chemother. 2012 Jun;56(6):3288-97. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Piperaquine tetraphosphate Related Classifications
HY-118865 Related Classifications
Powered by Bioz