Piperaquine-d6 tetraphosphate
Piperaquine-d6 (tetraphosphate) is the deuterium labeled Piperaquine tetraphosphate. Piperaquine tetraphosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C29H38D6Cl2N6O16P4
- Masse moléculaire:933.53
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Parasite
More
Activité biologique
|
Plasmodium |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 911061-10-4
-
Masse moléculaire 933.53
-
Formule C29H38D6Cl2N6O16P4
-
SMILES
ClC1=CC2=C(C=C1)C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])C([2H])([2H])N4CCN(C5=CC=NC6=C5C=CC(Cl)=C6)CC4)=CC=N2.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Moore BR, et, al. Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother. 2008 Jan; 52(1): 306-11. [Content Brief]
[3]. Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65(1): 75-87. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Piperaquine-d6 tetraphosphate Related Classifications
HY-118865S Related Classifications
Powered by Bioz