Piperaquine-d6
Piperaquine-d6 is the deuterium labeled Piperaquine. Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin.
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- CAS. Nr.: 1261394-71-1
- Formel: C29H26D6Cl2N6
- Molecular Weight:541.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1261394-71-1
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Unlabeled Cas 911061-10-4
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Molecular Weight 541.55
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Formel C29H26D6Cl2N6
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SMILES
ClC1=CC2=C(C=C1)C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])C([2H])([2H])N4CCN(C5=CC=NC6=C5C=CC(Cl)=C6)CC4)=CC=N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Moore BR, et, al. Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother. 2008 Jan; 52(1): 306-11. [Content Brief]
[3]. Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65(1): 75-87. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Piperaquine-d6 Related Classifications
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