2. Signaling Pathways
  3. Apoptosis
  4. TNF Receptor
  5. TNFRSF4 Isoform
  6. TNFRSF4 Agonist

TNFRSF4 Agonist

TNFRSF4 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-P992368
    HLX51
    		Agonist
    HLX51 is a regulatory T cell inhibitor and OX40/CD134/TNFRSF4 agonist with tumour growth inhibitory activity. HLX51 inhibits regulatory T cell differentiation and activity, relieves tumour microenvironment immunosuppression, enhances effector T cell function. HLX51 competitively binds OX40, activates OX40, promotes immune cell proliferation and T cell killing ability. HLX51 modulates immune cell function to inhibit tumour growth. HLX51 can be used for the research of advanced/metastatic solid tumours and lymphomas.