Dystrophin Inhibitor
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Zotadirsen
0 ImagesCat. No.: HY-177972Zotadirsen is the core component of the AOC drug Delpacibart zotadirsen (AOC1044) (HY-177564), consisting of a phosphorodiamidate morpholino oligonucleotide (PMO) targeting exon 44 of the dystrophin gene and an SMCC linker (HY-42360). Upon conjugation with the anti-TfR1 antibody Delpacibart (HY-P990051), Zotadirsen exerts splicing regulatory activity and mediates exon skipping. Zotadirsen can be used in studies related to AOC synthesis.
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FITC-labeled Drisapersen sodium
0 ImagesCat. No.: HY-150237FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.
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FAM labled Zotadirsen
0 ImagesCat. No.: HY-177972BFAM labled Zotadirsenis a FAM labled Zotadirsen.
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Cy3 labled Zotadirsen
0 ImagesCat. No.: HY-177972CCy3 labled Zotadirsen is a Cy3 labled Zotadirsen.
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Renadirsen
0 ImagesCat. No.: HY-177658CAS No.: 1782108-31-9Synonyms: DS-5141bRenadirsen is an antisense oligonucleotide that induces robust Exon 45 skipping for Dystrophin in vivo.
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Nivudirsen sodium scrambled negative control
0 ImagesCat. No.: HY-177649BNivudirsen sodium scrambled negative control is the sequence scrambled negative control of Nivudirsen sodium.
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Rimigorsen
0 ImagesCat. No.: HY-177659CAS No.: 1196915-71-5Rimigorsen is an antisense oligonucleotide that induces skipping of exon 44 of the pre-mRNA encoding dystrophin in a Duchenne muscular dystrophy (DMD)
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Rimigorsen sodium
0 ImagesCat. No.: HY-177659ARimigorsen sodium is an antisense oligonucleotide that induces skipping of exon 44 of the pre-mRNA encoding dystrophin in a Duchenne muscular dystrophy (DMD)
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Renadirsen sodium scrambled negative control
0 ImagesCat. No.: HY-177658BRenadirsen sodium scrambled negative control is the sequence scrambled negative control of Renadirsen sodium.
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Renadirsen sodium
0 ImagesCat. No.: HY-177658ASynonyms: DS-5141b sodiumRenadirsen sodium is an antisense oligonucleotide that induces robust Exon 45 skipping for Dystrophin in vivo.
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Nivudirsen sodium
0 ImagesCat. No.: HY-177649ANivudirsen sodium is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
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Rimigorsen sodium scrambled negative control
0 ImagesCat. No.: HY-177659BRimigorsen sodium scrambled negative control is the sequence scrambled negative control of Rimigorsen sodium.
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Nivudirsen
0 ImagesCat. No.: HY-177649CAS No.: 3053113-45-1Nivudirsen is an antisense oligonucleotide that can promote the synthesis of functional dystrophin protein.
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Unconjugated/naked Zotadirsen (without SMCC linker)
0 ImagesCat. No.: HY-177972DUnconjugated/naked Zotadirsen (without SMCC linker) represents the nucleic acid component of Zotadirsen (HY-177972), lacking both the amino group and the SMCC linker. Unconjugated/naked Zotadirsen (without SMCC linker) can be used for the synthesis of AOC reagents.
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