Soluble epoxide hydrolase Inhibitor
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UC-1728
0 ImagesSynonyms: t-TUCBUC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver.
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sEH inhibitor-7
0 ImagessEH inhibitor-7 is an sEH inhibitor, with an IC50 of 0.15 μM against mouse sEH and an IC50 of 6.2 μM against h-sEH. sEH inhibitor-7 can be used in studies related to hypertension and inflammation.
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sEH-IN-24
0 ImagesCat. No.: HY-183545CAS No.: 3121405-85-1sEH-IN-24 is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.9 nM. sEH-IN-24 inhibits the pro-inflammatory cytokines TNF-α and IL-6. sEH-IN-24 exhibits anti-inflammatory effects and exerts analgesic activity in vivo. sEH-IN-24 prevents pancreatic edema, inflammation and parenchymal atrophy. sEH-IN-24 can be used for the research of acute pancreatitis.
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SH-11037
0 ImagesCat. No.: HY-182372CAS No.: 1638153-78-2SH-11037 is a potent inhibitor of soluble epoxide hydrolase (sEH) and docks to the substrate binding cleft in the sEH hydrolase domain. SH-11037 dose-dependently suppresses angiogenesis in the choroidal sprouting assay ex vivo and inhibited ocular developmental angiogenesis in zebrafish larvae. SH-11037 reduces choroidal neovascularisation lesion volume in the laser-induced CNV mouse model. SH-11037 synergises with anti-VEGF treatments in vitro and in vivo. SH-11037 induces G2/M phase blockade and retains retinal endothelial cell viability at active concentrations without overt toxicity. SH-11037 can be used for the research of retinal neovascularization and ocular neovascularization.
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Moracin M 3'-O-β-D-glucopyranoside
0 ImagesCat. No.: HY-N21974CAS No.: 152041-26-4Moracin M 3'-O-β-D-glucopyranoside is a natural product with multiple activities such as hypoglycemic and antitumor effects. Moracin M 3'-O-β-D-glucopyranoside acts as an inhibitor of mushroom tyrosinase with an IC50 of 127.5 μM, and also functions as an inhibitor of soluble epoxide hydrolase with an IC50 of 7.7 μM. Moracin M 3'-O-β-D-glucopyranoside can be used in studies related to hyperglycemia and skin tumors.
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sEH-IN-26
0 ImagessEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases.
