3121405-85-1
Chemical Structure
sEH-IN-24
- CAS No.: 3121405-85-1
- Formula:C28H39NO6
- Molecular Weight:485.61
InChIKey: FLMWPTNUQHOKEI-OAQYLSRUSA-N
SMILES: CC([C@@H]1C2=C(OC3=C1C(C(C)(C(C3(C)C)=O)C)=O)C=C(C=C2OCCCN4CCOCC4)OC)C
Biological Activity: sEH-IN-24 is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.9 nM. sEH-IN-24 inhibits the pro-inflammatory cytokines TNF-α and IL-6. sEH-IN-24 exhibits anti-inflammatory effects and exerts analgesic activity in vivo. sEH-IN-24 prevents pancreatic edema, inflammation and parenchymal atrophy. sEH-IN-24 can be used for the research of acute pancreatitis[1].
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sEH-IN-24 | sEH-IN-24 is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.9 nM. sEH-IN-24 inhibits the pro-inflammatory cytokines TNF-α and IL-6. sEH-IN-24 exhibits anti-inflammatory effects and exerts analgesic activity in vivo. sEH-IN-24 prevents pancreatic edema, inflammation and parenchymal atrophy. sEH-IN-24 can be used for the research of acute pancreatitis. | |||||||||||||||||||||
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Keywords
