2. Metabolic Enzyme/Protease
  3. Epoxide Hydrolase
  4. sEH inhibitor-7

sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.

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sEH inhibitor-7 Chemical Structure

sEH inhibitor-7 Chemical Structure

CAS No. : 340221-20-7

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 66 In-stock
Solution
10 mM * 1 mL in DMSO USD 66 In-stock
Solid
5 mg USD 60 In-stock
10 mg USD 100 In-stock
25 mg USD 200 In-stock
50 mg USD 300 In-stock
100 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

sEH inhibitor-7 Related Antibodies

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Description

sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation[1].

Molecular Weight

247.33

Formula

C15H21NO2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC1=CC=C(OC)C=C1)CC2CCCCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (404.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0432 mL 20.2159 mL 40.4318 mL
5 mM 0.8086 mL 4.0432 mL 8.0864 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0432 mL 20.2159 mL 40.4318 mL 101.0795 mL
5 mM 0.8086 mL 4.0432 mL 8.0864 mL 20.2159 mL
10 mM 0.4043 mL 2.0216 mL 4.0432 mL 10.1080 mL
15 mM 0.2695 mL 1.3477 mL 2.6955 mL 6.7386 mL
20 mM 0.2022 mL 1.0108 mL 2.0216 mL 5.0540 mL
25 mM 0.1617 mL 0.8086 mL 1.6173 mL 4.0432 mL
30 mM 0.1348 mL 0.6739 mL 1.3477 mL 3.3693 mL
40 mM 0.1011 mL 0.5054 mL 1.0108 mL 2.5270 mL
50 mM 0.0809 mL 0.4043 mL 0.8086 mL 2.0216 mL
60 mM 0.0674 mL 0.3369 mL 0.6739 mL 1.6847 mL
80 mM 0.0505 mL 0.2527 mL 0.5054 mL 1.2635 mL
100 mM 0.0404 mL 0.2022 mL 0.4043 mL 1.0108 mL
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sEH inhibitor-7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sEH inhibitor-7340221-20-7sEH inhibitor7sEH inhibitor 7Epoxide Hydrolasemetabolismendogenous chemical mediatorsblood pressureinflammationInhibitorinhibitorinhibit

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