sEH inhibitor-7
Based on 1 Customer Validation
sEH inhibitor-7 is an sEH inhibitor, with an IC50 of 0.15 μM against mouse sEH and an IC50 of 6.2 μM against h-sEH. sEH inhibitor-7 can be used in studies related to hypertension and inflammation.
For research use only. We do not sell to patients.
- Purity: 99.50%
- CAS No.: 340221-20-7
- Formula: C15H21NO2
- Molecular Weight:247.33
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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sEH 0.15-6.2 μM (IC50) |
sEH inhibitor-7 (Compound c-2) (5 min) potently inhibits recombinant murine sEH with an IC50 of 0.15 μM and recombinant human sEH with an IC50 of 6.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 340221-20-7
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Appearance Solid
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Molecular Weight 247.33
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Formula C15H21NO2
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Color Off-white to light yellow
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SMILES
O=C(NC1=CC=C(OC)C=C1)CC2CCCCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (404.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0432 mL | 20.2159 mL | 40.4318 mL | 101.0795 mL |
| 5 mM | 0.8086 mL | 4.0432 mL | 8.0864 mL | 20.2159 mL | |
| 10 mM | 0.4043 mL | 2.0216 mL | 4.0432 mL | 10.1080 mL | |
| 15 mM | 0.2695 mL | 1.3477 mL | 2.6955 mL | 6.7386 mL | |
| 20 mM | 0.2022 mL | 1.0108 mL | 2.0216 mL | 5.0540 mL | |
| 25 mM | 0.1617 mL | 0.8086 mL | 1.6173 mL | 4.0432 mL | |
| 30 mM | 0.1348 mL | 0.6739 mL | 1.3477 mL | 3.3693 mL | |
| 40 mM | 0.1011 mL | 0.5054 mL | 1.0108 mL | 2.5270 mL | |
| 50 mM | 0.0809 mL | 0.4043 mL | 0.8086 mL | 2.0216 mL | |
| 60 mM | 0.0674 mL | 0.3369 mL | 0.6739 mL | 1.6847 mL | |
| 80 mM | 0.0505 mL | 0.2527 mL | 0.5054 mL | 1.2635 mL | |
| 100 mM | 0.0404 mL | 0.2022 mL | 0.4043 mL | 1.0108 mL |