2. Signaling Pathways
  3. GPCR/G Protein
  4. GLP Receptor
  5. GLP-1 Isoform
  6. GLP-1 Modulator

GLP-1 Modulator

GLP-1 Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-143312
    V-0219
    		Modulator 99.90%
    V-0219 is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 potentiates glucose-dependent insulin secretion. V-0219 improves glucose handling in normal and diabetic rodents. V-0219 can be used for the research of obesity-associated diabetes.
  • HY-143312A
    V-0219 hydrochloride
    		Modulator 99.39%
    V-0219 hydrochloride is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 hydrochloride potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 hydrochloride potentiates glucose-dependent insulin secretion. V-0219 hydrochloride improves glucose handling in normal and diabetic rodents. V-0219 hydrochloride can be used for the research of obesity-associated diabetes.