2. Signaling Pathways
  3. Metabolic Enzyme/Protease
    PI3K/Akt/mTOR
  4. IPK Superfamily
  5. Inositol hexakisphosphate kinase Isoform
  6. Inositol hexakisphosphate kinase Inhibitor

Inositol hexakisphosphate kinase Inhibitor

Inositol hexakisphosphate kinase Inhibitors (3):

Cat. No. 상품명 효과 Purity
  • HY-171099
    SC-919
    		Inhibitor 98.68%
    SC-919 is an orally active IP6K inhibitor, with an IC50 of < 5.2 nM against IP6K1, < 3.8 nM against IP6K2, and 0.65 nM against IP6K3. By inhibiting the activity of IP6K, SC-919 reduces intracellular IP7 levels, thereby suppressing XPR1-mediated cellular phosphate efflux. SC-919 increases intracellular phosphate and ATP levels while reducing phosphate entry into the bloodstream, thus decreasing plasma phosphate levels. SC-919 can be used in research related to chronic kidney disease and hyperphosphatemia.
  • HY-185141
    IP6K-IN-2
    		Inhibitor
    IP6K-IN-2 is an inositol hexakisphosphate kinase (IP6K1) inhibitor that inhibits IP6K1 enzyme activity with an IC50 value of 110 nM. IP6K-IN-2 can be used for the research of neurological disease and CNS disorders.
  • HY-161032
    IP6K2-IN-1
    		Inhibitor 99.47%
    IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC50 value of 0.55 μM. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors.