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Isotope-Labeled Compounds
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Isotope-Labeled Compounds Related Products (11098)
Related Products (11098)
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2-Iodoaniline-13C6
0 ImagesCat. No.: HY-W007318SCAS No.: 1261170-87-9Synonyms: 2-Iodophenylamine-13C62-Iodoaniline-13C6 is the 13C labeled 2-Iodoaniline. -
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Docosanoic acid-d4-2
0 ImagesSynonyms: Behenic acid-d4-2Docosanoic acid-d4-2 (Behenic acid-d4-2) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans. -
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(3S,5R)-Rosuvastatin-d6 sodium
0 ImagesCat. No.: HY-W654338CAS No.: 2734920-03-5Rosuvastatin Sodium Salt-d6 is the deuterium labeled Rosuvastatin Sodium Salt. -
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Pentyl carbonochloridate-d11
0 ImagesCat. No.: HY-W015603SCAS No.: 1398065-67-2Pentyl carbonochloridate-d11 is the deuterium labeled Pentyl carbonochloridate. -
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Benz[a]anthracen-3-ol-d11
0 ImagesCat. No.: HY-142876SBenz[a]anthracen-3-ol-d11 is the deuterium labeled Benz[a]anthracen-3-ol. -
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Bivamelagon-d8
0 ImagesCat. No.: HY-153660SSynonyms: MC-4R Agonist 2-d8Bivamelagon-d8 (MC-4R Agonist 2-d8) is the deuterium labeled Bivamelagon (HY-153660). Bivamelagon (MC-4R Agonist 2) is an orally active MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes. -
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N-Nitrosomorpholine-d4
0 ImagesCat. No.: HY-131123SCAS No.: 61578-30-1N-Nitrosomorpholine-d4 is the deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen. -
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Methyl 5-methylisoxazole-3-carboxylate-d4
0 ImagesCat. No.: HY-W743061CAS No.: 2517728-88-8Synonyms: methyl 5-methyl-1,2-oxazole-3-carboxylate-d4Methyl 5-methylisoxazole-3-carboxylate-d4 (methyl 5-methyl-1,2-oxazole-3-carboxylate-d4) is the deuterium labeled Methyl 5-methylisoxazole-3-carboxylate (HY-W017589). -
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Latanoprost ethyl amide-d4
0 ImagesCat. No.: HY-129934SSynonyms: Lat-NEt-d4Latanoprost ethyl amide-d4 (Lat-NEt-d4) is deuterium labeled Latanoprost ethyl amide. Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.1 Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides. -
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Tirofiban-d9
0 ImagesCat. No.: HY-17369BSCAS No.: 1332075-40-7Synonyms: L700462-d9; MK383-d9Tirofiban-d9 is deuterium labeled Tirofiban. -
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Oxidized 18:2 cholesterol-d7
0 ImagesCat. No.: HY-167582SCAS No.: 2936622-60-3Oxidized 18:2 cholesterol-d7 is deuterium labeled Oxidized 18:2 cholesterol. -
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Ticlopidine-d6 hydrochloride
0 ImagesCat. No.: HY-166530STiclopidine-d6 hydrochloride is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine (PCR 5332) hydrochloride, an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine hydrochloride blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine hydrochloride is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine hydrochloride inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively. -
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QTALVELV-{Lys-13C6,15N2} TFA
0 ImagesCat. No.: HY-P11873SPurity: 98.18%QTALVELV-{Lys-13C6,15N2} TFA is the 13C- and 15N-labeled QTALVELV TFA. -
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(2,4,6-Trichlorophenoxy)acetic acid-13C6
0 ImagesCat. No.: HY-W749012(2,4,6-Trichlorophenoxy)acetic acid-13C6 is the 13C labeled isotope of (2,4,6-Trichlorophenoxy)acetic acid. -
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β-Ionone-13C3
0 ImagesCat. No.: HY-W015084Sβ-Ionone-13C3 is the 13C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity. -
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D-erythro-Ritalinic acid-d10
0 ImagesCat. No.: HY-132412SCAS No.: 1330166-48-7D-erythro-Ritalinic acid-d10 is the deuterium labeled D-erythro-Ritalinic acid. -
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Carbenoxolone-d4
0 ImagesCat. No.: HY-B1588SPurity: 99.28%Carbenoxolone-d4 is the d4 labeled Carbenoxolone (HY-B1588). Carbenoxolone is a blood-brain barrier-permeable Pannexin1 inhibitor, gap junction (Gap junction) blocker, and β-amyloid 42 inhibitor. Carbenoxolone modulates voltage-gated currents of wild-type and mutant Panx1, and inhibits stimulus-activated Panx1 channel function. Carbenoxolone interacts with stable residues of β-amyloid 42 peptides, fibrils and oligomers, thereby inhibiting their aggregation. Carbenoxolone alleviates liver fibrosis. Carbenoxolone exerts neuroprotective and nootropic effects. Carbenoxolone can be used in studies related to Alzheimer's disease and liver fibrosis. -
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Enterolactone-13C3
0 ImagesCat. No.: HY-W778286CAS No.: 918502-72-4Enterolactone-13C3 is the 13C-labeled Enterolactone (HY-108692). Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. -
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Berotralstat-d4-1
0 ImagesCat. No.: HY-109127SSynonyms: BCX7353-d4-1Berotralstat-d4-1 (BCX7353-d4-1) is the deuterium labeled Berotralstat (HY-109127). Berotralstat (BCX7353) is an orally active plasma kallikrein inhibitor. Berotralstat can reduce brain edema and is being studied for glioblastoma and hereditary angioedema. -
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(S)-Verapamil-d7 (hydrochloride)
0 ImagesCat. No.: HY-135336ASCAS No.: 2967473-85-2Synonyms: (S)-(-)-Verapamil-d7 (hydrochloride)(S)-Verapamil-d7 (hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. -
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