Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
All Product Categories
-
Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
-
Cefetamet-d3
0 ImagesCat. No.: HY-W743473Synonyms: Ro 15-8074-d3; Deacetoxycefotaxime-d3Cefetamet-d3 (Ro 15-8074-d3; Deacetoxycefotaxime-d3) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis.
-
L-Arginine-13C,d4(dihydrochloride)
0 ImagesCat. No.: HY-W654058L-Arginine-13C,d4 (dihydrochloride) is 13C labeled L-Arginine (dihydrochloride).
-
L-Threonine-13C4,15N,d5
0 ImagesCat. No.: HY-N0658S2CAS No.: 2378755-51-0L-Threonine-13C4,15N,d5 is the deuterium, 13C-, and 15-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.
-
(E/Z)-Chlorprothixene-d6 hydrochloride
0 ImagesCat. No.: HY-B0274CSCAS No.: 1246832-91-6(E/Z)-Chlorprothixene-d6 hydrochloride is the deuterium labeled (E/Z)-Chlorprothixene hydrochloride.
-
Cletoquine-d4-1
0 ImagesCat. No.: HY-135810S1CAS No.: 1216461-56-1Synonyms: Desethylhydroxychloroquine-d4-1Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment.
-
Ethyl chrysanthemate-d6
0 ImagesCat. No.: HY-W753976Ethyl chrysanthemate-d6 is the deuterium labeled Ethyl chrysanthemate (HY-N7100). Ethyl chrysanthemate is an allelochemical compound used as an attractant.
-
Rofecoxib-d5
0 ImagesCat. No.: HY-17372SCAS No.: 544684-93-7Rofecoxib-d5 is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).
-
Glimepiride-d4-1
0 ImagesSynonyms: Glimperide-d4; HOE-490-d4Glimepiride-d4-1 is deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
-
L-Phenylalanine-13C-1
0 ImagesCat. No.: HY-N0215S16CAS No.: 136056-01-4Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C-1L-Phenylalanine-13C-1 ((S)-2-Amino-3-phenylpropionic acid-13C-1) is the 13C-labeled L-Phenylalanine (HY-N0215). L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (Kb of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
-
N-Nitrosoanatabine-d3
0 ImagesCat. No.: HY-145476S2Synonyms: N-NAT-d3; N'-Nitrosoanatabine-d3N-Nitrosoanatabine-d3 (N-NAT-d3; N'-Nitrosoanatabine-d3) is the deuterium labeled N-Nitrosoanatabine (HY-145476). N-Nitrosoanatabine (N-NAT; N'-Nitrosoanatabine) is a tobacco-specific nitrosamine that exists in tobacco, tobacco products and e-cigarettes.
-
Guanidine-13C hydrochloride
0 ImagesCat. No.: HY-B0178AS2CAS No.: 286013-04-5Synonyms: Guanidinium-13C chloride; Aminoformamidine-13C hydrochlorideGuanidine-13C hydrochloride (Guanidinium-13C chloride) is the 13C-labeled Guanidine hydrochloride (HY-B0178A). 6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. Guanidine hydrochloride is a strong protein denaturant. Guanidine hydrochloride causes proteins to assume a random coil conformation.
-
Propane-1,2,3-triyl tripalmitate-d98
0 ImagesCat. No.: HY-W013061S6CAS No.: 1219803-85-6Propane-1,2,3-triyl tripalmitate-d98 is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
-
Chenodeoxycholic Acid-d7
0 ImagesCat. No.: HY-W712932Synonyms: CDCA-d7Chenodeoxycholic Acid-d7 (CDCA-d7) is the deuterium labeled Chenodeoxycholic Acid (HY-76847). Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
-
Boc-Leu-OH·H2O-d7
0 ImagesCat. No.: HY-W101495S3Boc-Leu-OH·H2O-d7 is the deuterium labeled Boc-Leu-OH·H2O.
-
Afatinib-d6 dimaleate
0 ImagesCat. No.: HY-10261ASSynonyms: BIBW 2992MA2-d6Afatinib-d6 (dimaleate) is the deuterium labeled Afatinib dimaleate. Afatinib dimaleate is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.
-
L-α-Phenyl-glycine-d5
0 ImagesL-α-Phenyl-glycine-d5 is the deuterium labeled L-α-Phenyl-glycine.
-
Tetraethylammonium bromide-d20
0 ImagesCat. No.: HY-W724370Synonyms: TEA bromide-d20Tetraethylammonium bromide-d20 (TEA bromide-d20) is the deuterium labeled Tetraethylammonium bromide (HY-W014408). Tetraethylammonium bromide is a quaternary ammonium salt consisting of a positively charged tetraethylammonium cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a reagent for the synthesis of various organic compounds, an electrolyte in electrochemical experiments, and a source of tetraethylammonium ions in biochemical and pharmacological research.
-
Mycophenolate Mofetil-d4 (hydrochloride)
0 ImagesCat. No.: HY-B0199ASSynonyms: RS 61443-d4 hydrochloride; TM-MMF-d4 hydrochlorideMycophenolate Mofetil-d4 hydrochloride is deuterated labeled Mycophenolate mofetil hydrochloride (HY-B0199A). Mycophenolate mofetil (RS 61443; TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection).
