2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10678):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0852S2
    Tebuconazole-d6
    Tebuconazole-d6 is a deuterium labeled Tebuconazole (HY-B0852). Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells.
    Tebuconazole-d<sub>6</sub>
  • HY-W009490S
    2,4-Dibromophenol-d3
    		99.5%
    2,4-Dibromophenol-d3 is the deuterium labeled 2,4-Dibromophenol.
    2,4-Dibromophenol-d<sub>3</sub>
  • HY-W338810S
    S-(5'-Adenosyl)-L-methionine-13C5 sulfate
    S-(5'-Adenosyl)-L-methionine-13C5 sulfate is a 13C-labeled S-(5'-Adenosyl)-L-methionine. S-(5'-Adenosyl)-L-methionine is a methyl donor and cofactor.
    S-(5'-Adenosyl)-L-methionine-<sup>13</sup>C<sub>5</sub> sulfate
  • HY-W007337S
    3-Bromopropan-1-ol-d6
    		98.5%
    3-Bromopropan-1-ol-d6 is the deuterium labeled 3-Bromopropan-1-ol (HY-W007337). 3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly upregulated during the estrus period in buffaloes. 3-Bromopropan-1-ol can be used in buffalo estrus research.
    3-Bromopropan-1-ol-d<sub>6</sub>
  • HY-17427S4
    Emtricitabine-d2
    Emtricitabine-d2 (BW1592-d2) is deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.
    Emtricitabine-d<sub>2</sub>
  • HY-113482S
    1β-Hydroxydeoxycholic acid-d5
    1β-Hydroxydeoxycholic Acid-d5 is the deuterium labeled 1β-Hydroxydeoxycholic Acid.
    1β-Hydroxydeoxycholic acid-d<sub>5</sub>
  • HY-Y0484S
    1-Indanamine-d9 hydrochloride
    1-Indanamine-d9 (1-Aminoindan-d9; 1-Aminoindane-d9; NSC 186227-d9; 1-Aminoindane-d9) hydrochloride is deuterium-labeled 1-Indanamine hydrochloride (HY-Y0484).
    1-Indanamine-d<sub>9</sub> hydrochloride
  • HY-B1418S2
    Tazobactam-15N,d2
    Tazobactam-15N,d2 (CL-298741-15N,d2) is 15N and deuterium labeled Tazobactam. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research.
    Tazobactam-<sup>15</sup>N<sub>,d<sub>2</sub>
  • HY-165704S
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium).
    2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d<sub>4</sub>
  • HY-W778555
    Diclofenamide-13C6
    Diclofenamide-13C6 is 13C-labeled Diclofenamide (HY-B0397).
    Diclofenamide-13C6
  • HY-B0168S
    Milnacipran-d10 hydrochloride
    		99.85%
    Milnacipran-d10 (hydrochloride) is the deuterium labeled Milnacipran hydrochloride (HY-B0168A). Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia).
    Milnacipran-d<sub>10</sub> hydrochloride
  • HY-146841S
    Lysophosphatidylcholine C19:0-d5
    Lecithin-cholesterol acyltransferase C19:0-d5 (19:0 lecithin-cholesterol acyltransferase-d5) is the deuterated form of lecithin-cholesterol acyltransferase C19:0 (HY-154830). Lecithin-cholesterol acyltransferase C19:0 is a lysophosphatidylcholine with a fully saturated C19 acyl chain. When lecithin-cholesterol acyltransferase C19:0 is combined with LPS (HY-D1056), it can induce the secretion of IL-1β by human monocyte-derived dendritic cells. Lecithin-cholesterol acyltransferase C19:0 can reduce the survival rate of dendritic cells derived from monocytes.
    Lysophosphatidylcholine C19:0-d<sub>5</sub>
  • HY-W653978
    Cinacalcet-d4 hydrochloride
    Cinacalcet-d4 (AMG-073-d4) hydrochlorideis deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
    Cinacalcet-d<sub>4</sub> hydrochloride
  • HY-W009204S1A
    Fmoc-Ala-OH-d3 hydrate
    Fmoc-Ala-OH-d3 hydrate is the deuterium labeled Fmoc-Ala-OH-3,3,3.
    Fmoc-Ala-OH-d<sub>3</sub> hydrate
  • HY-B0511S3
    Biotin-13C5
    Biotin-13C5 (Vitamin B7-13C5) is 13C labeled Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
    Biotin-<sup>13</sup>C<sub>5</sub>
  • HY-W101602S
    2-Isobutyl-3-methylpyrazine-dsub>3
    2-Isobutyl-3-methylpyrazine-d3 is deuterated labeled 2-Isobutyl-3-methylpyrazine.
    2-Isobutyl-3-methylpyrazine-dsub>3</sub>
  • HY-B0072S
    Tropisetron-d5
    Tropisetron-d5 (SDZ-ICS-930-d5 (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT3R antagonists with a Ki of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor (α7 nAChR) with an EC50 of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects.
    Tropisetron-d<sub>5</sub>
  • HY-112251S
    D-Lin-MC3-DMA-13C3
    D-Lin-MC3-DMA-13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
    D-Lin-MC3-DMA-<sup>13</sup>C<sub>3</sub>
  • HY-17624S
    Framycetin-d2
    Framycetin-d2 (Neomycin B-d2) is the deuterium labeled Framycetin (HY-17624). Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.
    Framycetin-d<sub>2</sub>
  • HY-B0281AS
    Ranitidine-d6 hydrochloride
    Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice.
    Ranitidine-d<sub>6</sub> hydrochloride