1. Signaling Pathways
  2. PROTAC
  3. LYTACs

LYTACs

Lysosome-targeting chimeras

Lysosome targeting chimera (LYTAC) degrades target proteins via lysosomal pathway rather than common proteasome pathway. LYTAC degrades target proteins by binding to asialoglycoprotein receptor on lysosomal through its asialoglycoprotein receptor ligand. Another side of LYTAC is usually an antibody so it can bind to target protein for degradation.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-153527
    GalNac-L96 analog 1159408-72-6
    GalNAc-L96 analog is an intermediate in the synthesis of the asialoglycoprotein receptor (ASGPR) ligand GalNAc-L96 (HY-147012).
    GalNac-L96 analog
  • HY-145013
    tri-GalNAc-COOH (acetylation) 3008204-26-7
    tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC.
    tri-GalNAc-COOH (acetylation)
Cat. No. Product Name / Synonyms Application Reactivity