2. シグナル伝達
  3. GPCR/G Protein
  4. Natriuretic Peptide Receptor (NPR)

Natriuretic Peptide Receptor (NPR)

Natriuretic Peptide Receptor; NPR; NPR-A; NPR-B; NPR-C

Natriuretic peptide receptors can be divided into three types: NPR-A, NPR-B (guanylate cyclase-A and guanylate cyclase-B) and NPR-C. All three receptors have an effect on biological second messengers. NPR-A and NPR-B are guanylate cyclase receptors, and their activation can lead to increased cGMP levels, while the activation of NPR-C can lead to the inhibition of adenylate cyclase activity and increased phospholipase C activity. Natriuretic peptide receptors play an important role in the regulation of blood pressure and cardiovascular homeostasis[1].

Natriuretic Peptide Receptor (NPR) 関連製品 (28):

製品番号 製品名 製品効果 純度 構造式
  • HY-P3763
    Atrial Natriuretic Peptide (7-28), human, canine
    Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag.
    Atrial Natriuretic Peptide (7-28), human, canine
  • HY-P5978
    Atriopeptin III (rat)
    Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure.
    Atriopeptin III (rat)
  • HY-P1573
    Brain Natriuretic Peptide-45, rat
    Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
    Brain Natriuretic Peptide-45, rat
  • HY-P3759
    BNP (22-46), Pro (Human) Activator
    BNP (22-46), Pro (Human) is an peptide . BNP (22-46), Pro (Human) can be used for the research of cardiac dysfunction.
    BNP (22-46), Pro (Human)
  • HY-P3774
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels.
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat
  • HY-120147
    Ethiazide
    Ethiazide is a thiazole diuretic which inhibits renal reabsorption of sodium and water, thereby increasing urine excretion, reducing fluid retention, and lowering blood volume and blood pressure. Ethiazide can be used for cardiovascular research.
    Ethiazide
  • HY-P3772
    [Mpr7, DAla9] ANP (7-28), amide, rat
    [Mpr7, DAla9] ANP (7-28), amide, rat is an atrial peptide.
    [Mpr7, DAla9] ANP (7-28), amide, rat
  • HY-P991121
    Baloncibart Inhibitor
    Baloncibart is a human IgG4K antibody targeting NPR1. The corresponding isotype control is: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Baloncibart