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Art. -Nr.: HY-W092067

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6-Hydroxyisatin

Name: 6-Hydroxyisatin
Brand: MedChemExpress
SKU: HY-W092067
Price: 62.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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6-Hydroxyisatin is an atrial natriuretic peptide receptor (ANP receptor) inhibitor. 6-Hydroxyisatin exhibits inhibitory activity against ANP-stimulated particulate guanylyl cyclase activity in rat brain cell membranes.

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Reinheit : 95.86%
CAS. Nr.: 116569-08-5
Formel: C₈H₅NO₃
Molecular Weight:163.13

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

6-Hydroxyisatin Chemical Structure

CAS. Nr.: 116569-08-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

In Vitro

6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat brain membranes by 54.4%^[2].
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat heart membranes by 16.7%^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 116569-08-5
Appearance Solid
Molecular Weight 163.13
Formel C₈H₅NO₃
Color Orange to red
SMILES

O=C1NC2=C(C=CC(O)=C2)C1=O
Structure Classification
- Others
Initial Source
- Microorganism
Micromonospora carbonacea
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 2 mg/mL (12.26 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

6.1301 mL

30.6504 mL

61.3008 mL

5 mM

1.2260 mL

6.1301 mL

12.2602 mL

10 mM

0.6130 mL

3.0650 mL

6.1301 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Khaled A. Shaaban, et al. Structure elucidation and synthesis of
hydroxylated isatins from Streptomycetes. Z. Naturforsch. 2016; 71(12)b: 1191-1198

[2]. Medvedev AE, et al. Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclase. Biochem Pharmacol. 1999;57(8):913-915. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	6.1301 mL	30.6504 mL	61.3008 mL	153.2520 mL
	5 mM	1.2260 mL	6.1301 mL	12.2602 mL	30.6504 mL
	10 mM	0.6130 mL	3.0650 mL	6.1301 mL	15.3252 mL

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

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6-Hydroxyisatin

Biologische Aktivität

Beschreibung

In Vitro

Chemical Information

Lösungsmittel & Löslichkeit

In Vitro:

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

6-Hydroxyisatin Related Classifications

HY-W092067 Related Classifications

Bioz

Keywords

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