6-Hydroxyisatin
Based on 1 Customer Validation
6-Hydroxyisatin is an atrial natriuretic peptide receptor (ANP receptor) inhibitor. 6-Hydroxyisatin exhibits inhibitory activity against ANP-stimulated particulate guanylyl cyclase activity in rat brain cell membranes.
For research use only. We do not sell to patients.
- Purity: 95.86%
- CAS No.: 116569-08-5
- Formula: C8H5NO3
- Molecular Weight:163.13
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat brain membranes by 54.4%[2].
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat heart membranes by 16.7%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 116569-08-5
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Appearance Solid
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Molecular Weight 163.13
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Formula C8H5NO3
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Color Orange to red
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SMILES
O=C1NC2=C(C=CC(O)=C2)C1=O
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Structure Classification
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Initial Source
Micromonospora carbonacea
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- 6-Hydroxyisatin
- 116569-08-5
- Natriuretic Peptide Receptor (NPR)
- DFT
- rat brain membranes
- atrial natriuretic peptide receptors
- keto/phenol tautomerism
- atrial natriuretic peptide
- rat heart membranes
- Sandmeyer’s procedure
- UV/Vis absorption
- Streptomyces sp. strain B1848
- particulate guanylyl cyclase
- Inhibitor
- inhibitor
- inhibit