1. Anti-infection
  2. Bacterial
  3. Zidebactam

Zidebactam (Synonyms: WCK-5107)

Cat. No.: HY-120859
Handling Instructions

Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.

For research use only. We do not sell to patients.

Zidebactam Chemical Structure

Zidebactam Chemical Structure

CAS No. : 1436861-97-0

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Description

Zidebactam (WCK-5107) is a potent β-lactamase inhibitor[1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL[2].

IC50 & Target

IC50: 0.26 μg/mL (P. aeruginosa PAO1 PBP2)[2]

In Vitro

Zidebactam (WCK-5107) inhibits WT Enterobacteriaceae with a MIC50 of 0.25 mg/L. Zidebactam alone exhibits variable activity when tested against E. coli (MIC50/90 0.12/0.12  mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25  mg/L)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

391.40

Formula

C₁₃H₂₁N₅O₇S

CAS No.

1436861-97-0

SMILES

O=C([[email protected]@H]1CCCNC1)NNC([[email protected]@H]2CC[[email protected]@H]3C[[email protected]]2C(N3OS(=O)(O)=O)=O)=O

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Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Zidebactam
Cat. No.:
HY-120859
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Zidebactam

Cat. No.: HY-120859