1. Anti-infection
  2. Bacterial
  3. Zidebactam

Zidebactam (Synonyms: WCK-5107)

Cat. No.: HY-120859
Handling Instructions

Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.

For research use only. We do not sell to patients.

Zidebactam Chemical Structure

Zidebactam Chemical Structure

CAS No. : 1436861-97-0

Size Price Stock Quantity
10 mM * 1 mL in Water USD 605 In-stock
Estimated Time of Arrival: December 31
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Zidebactam:

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Description

Zidebactam (WCK-5107) is a potent β-lactamase inhibitor[1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL[2].

IC50 & Target

IC50: 0.26 μg/mL (P. aeruginosa PAO1 PBP2)[2]

In Vitro

Zidebactam (WCK-5107) inhibits WT Enterobacteriaceae with a MIC50 of 0.25 mg/L. Zidebactam alone exhibits variable activity when tested against E. coli (MIC50/90 0.12/0.12  mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25  mg/L)[1].

Clinical Trial
Molecular Weight

391.40

Formula

C₁₃H₂₁N₅O₇S

CAS No.

1436861-97-0

SMILES

O=C([[email protected]@H]1CCCNC1)NNC([[email protected]@H]2CC[[email protected]@H]3C[[email protected]]2C(N3OS(=O)(O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (127.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5549 mL 12.7747 mL 25.5493 mL
5 mM 0.5110 mL 2.5549 mL 5.1099 mL
10 mM 0.2555 mL 1.2775 mL 2.5549 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Zidebactam
Cat. No.:
HY-120859
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